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CDT1 chromatin licensing and DNA replication factor 1 [ Gallus gallus (chicken) ]

Gene ID: 426254, updated on 5-Mar-2024

Summary

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Symbol
CDT1provided by CGNC
Full Name
chromatin licensing and DNA replication factor 1provided by CGNC
Primary source
CGNC:10323
See related
Ensembl:ENSGALG00010007887
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 11
Exon count:
10
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 11 NC_052542.1 (18105653..18109425)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 11 NC_052583.1 (18453347..18457119)

Chromosome 11 - NC_052542.1Genomic Context describing neighboring genes Neighboring gene cytosolic thiouridylase subunit 2 Neighboring gene piezo type mechanosensitive ion channel component 1 Neighboring gene adenine phosphoribosyltransferase Neighboring gene galactosamine (N-acetyl)-6-sulfatase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA polymerase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA replication checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA replication preinitiation complex assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated DNA replication initiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA replication factor Cdt1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052542.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    18105653..18109425
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_423919.8 → XP_423919.5  DNA replication factor Cdt1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XQ29, A0A8V0XUF1
    Related
    ENSGALP00010010315.1, ENSGALT00010018765.1
    Conserved Domains (3) summary
    cd08674
    Location:214 → 399
    Cdt1_m; The middle winged helix fold of replication licensing factor Cdt1 binds geminin to inhibit binding of the MCM complex to origins of replication and DNA
    cd08767
    Location:456 → 578
    Cdt1_c; The C-terminal fold of replication licensing factor Cdt1 is essential for Cdt1 activity and directly interacts with MCM2-7 helicase
    PRK14951
    Location:1 → 147
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052583.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    18453347..18457119
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040681446.2 → XP_040537380.1  DNA replication factor Cdt1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XUF1
    Conserved Domains (3) summary
    cd08674
    Location:214 → 399
    Cdt1_m; The middle winged helix fold of replication licensing factor Cdt1 binds geminin to inhibit binding of the MCM complex to origins of replication and DNA
    cd08767
    Location:456 → 578
    Cdt1_c; The C-terminal fold of replication licensing factor Cdt1 is essential for Cdt1 activity and directly interacts with MCM2-7 helicase
    PRK14951
    Location:1 → 147
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional

  2. XM_040681447.2 → XP_040537381.1  DNA replication factor Cdt1 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XUF1
    Conserved Domains (3) summary
    cd08674
    Location:213 → 398
    Cdt1_m; The middle winged helix fold of replication licensing factor Cdt1 binds geminin to inhibit binding of the MCM complex to origins of replication and DNA
    cd08767
    Location:455 → 577
    Cdt1_c; The C-terminal fold of replication licensing factor Cdt1 is essential for Cdt1 activity and directly interacts with MCM2-7 helicase
    PRK14951
    Location:1 → 147
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
Nucleotide Protein
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