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MAP2K4 mitogen-activated protein kinase kinase 4 [ Pan troglodytes (chimpanzee) ]

Gene ID: 455065, updated on 29-Mar-2024

Summary

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Official Symbol
MAP2K4provided by VGNC
Official Full Name
mitogen-activated protein kinase kinase 4provided by VGNC
Primary source
VGNC:VGNC:9364
Locus tag
CK820_G0021184
See related
Ensembl:ENSPTRG00000008783
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See MAP2K4 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 19 NC_072417.2 (58545437..58668204, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 17 NC_072415.1 (56729892..56852659, complement)

Chromosome 19 - NC_072417.2Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 44 Neighboring gene uncharacterized LOC104002916 Neighboring gene myocardin Neighboring gene dynein light chain Tctex-type 1-like Neighboring gene small nucleolar RNA U3 Neighboring gene microRNA mir-744 Neighboring gene zinc finger protein 18 Neighboring gene dynein axonemal heavy chain 9 Neighboring gene uncharacterized LOC129137697 Neighboring gene shisa family member 6 Neighboring gene spidroin-2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables JUN kinase kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dual specificity mitogen-activated protein kinase kinase 4
XP_001163981.2
XP_009431008.1
XP_016787851.1
XP_063655091.1
XP_511831.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072417.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    58545437..58668204 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009432733.4 → XP_009431008.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X5

    See identical proteins and their annotated locations for XP_009431008.1

    Conserved Domains (1) summary
    cd06616
    Location:1 → 267
    PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

  2. XM_511831.8 → XP_511831.3  dual specificity mitogen-activated protein kinase kinase 4 isoform X1

    UniProtKB/TrEMBL
    A0A2I3S5T8, A0A2J8MGY6, A0A6D2XM93, K7APE5
    Related
    ENSPTRP00000081869.1
    Conserved Domains (1) summary
    cd06616
    Location:95 → 385
    PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

  3. XM_001163981.7 → XP_001163981.2  dual specificity mitogen-activated protein kinase kinase 4 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SCZ0, A0A2J8MGY5, A0A6D2Y882, H2QCA7
    Related
    ENSPTRP00000014968.5
    Conserved Domains (1) summary
    cd06616
    Location:106 → 396
    PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

  4. XM_063799021.1 → XP_063655091.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X3

  5. XM_016932362.4 → XP_016787851.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X2

    UniProtKB/TrEMBL
    A0A2I3SCZ0

RNA

  1. XR_675352.5 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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