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PSENEN presenilin enhancer, gamma-secretase subunit [ Pan troglodytes (chimpanzee) ]

Gene ID: 455962, updated on 29-Mar-2024

Summary

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Official Symbol
PSENENprovided by VGNC
Official Full Name
presenilin enhancer, gamma-secretase subunitprovided by VGNC
Primary source
VGNC:VGNC:55606
See related
Ensembl:ENSPTRG00000029038
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 20 NC_072418.2 (38871690..38873542)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 19 NC_072417.1 (38871717..38873569)

Chromosome 20 - NC_072418.2Genomic Context describing neighboring genes Neighboring gene lysine methyltransferase 2B Neighboring gene IGF like family receptor 1 Neighboring gene U2 small nuclear RNA auxiliary factor 1 like 4 Neighboring gene lin-37 DREAM MuvB core complex component Neighboring gene heat shock protein family B (small) member 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in Notch receptor processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of gamma-secretase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
gamma-secretase subunit PEN-2
Names
presenilin enhancer 2 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072418.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    38871690..38873542
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054673320.1 → XP_054529295.1  gamma-secretase subunit PEN-2

    UniProtKB/TrEMBL
    H2QG41

  2. XM_512600.7 → XP_512600.1  gamma-secretase subunit PEN-2

    See identical proteins and their annotated locations for XP_512600.1

    UniProtKB/TrEMBL
    H2QG41
    Related
    ENSPTRP00000018600.4
    Conserved Domains (1) summary
    pfam10251
    Location:7 → 99
    PEN-2; Presenilin enhancer-2 subunit of gamma secretase

  3. XM_001161441.6 → XP_001161441.1  gamma-secretase subunit PEN-2

    See identical proteins and their annotated locations for XP_001161441.1

    UniProtKB/TrEMBL
    H2QG41
    Conserved Domains (1) summary
    pfam10251
    Location:7 → 99
    PEN-2; Presenilin enhancer-2 subunit of gamma secretase

  4. XM_054673322.2 → XP_054529297.1  gamma-secretase subunit PEN-2

    UniProtKB/TrEMBL
    H2QG41
Nucleotide Protein
Heading Accession and Version

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