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ROR1 receptor tyrosine kinase like orphan receptor 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 456910, updated on 11-Apr-2024

Summary

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Official Symbol
ROR1provided by VGNC
Official Full Name
receptor tyrosine kinase like orphan receptor 1provided by VGNC
Primary source
VGNC:VGNC:11900
Locus tag
CK820_G0010403
See related
Ensembl:ENSPTRG00000024245
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (166808950..167216169, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (64082695..64490343)

Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene U7 small nuclear RNA Neighboring gene uncharacterized LOC107966977 Neighboring gene ubiquitin conjugating enzyme E2 U Neighboring gene U6 spliceosomal RNA Neighboring gene cofilin-1-like Neighboring gene large ribosomal subunit protein eL19-like Neighboring gene phosphoglucomutase 1 Neighboring gene U7 small nuclear RNA Neighboring gene EF-hand calcium binding domain 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of neuron projection development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
inactive tyrosine-protein kinase transmembrane receptor ROR1
XP_016775314.1
XP_016775318.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    166808950..167216169 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016919829.4 → XP_016775318.1  inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8NHJ3

  2. XM_016919825.4 → XP_016775314.1  inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3TWE1, A0A2J8NHJ5, A0A6D2VXM7, H2R908, K7CHI3
    Related
    ENSPTRP00000052236.4
    Conserved Domains (4) summary
    cd07467
    Location:166 → 307
    CRD_TK_ROR1; Cysteine-rich domain of tyrosine kinase-like orphan receptor 1
    smart00130
    Location:311 → 393
    KR; Kringle domain
    smart00410
    Location:66 → 148
    IG_like; Immunoglobulin like
    cd05090
    Location:467 → 749
    PTKc_Ror1; Catalytic domain of the Protein Tyrosine Kinase, Receptor tyrosine kinase-like Orphan Receptor 1
Nucleotide Protein
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