RFC1 replication factor C subunit 1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: RFC1provided by VGNC
Official Full Name: replication factor C subunit 1provided by VGNC
Primary source: VGNC:VGNC:2002
Locus tag: CK820_G0003758
See related: Ensembl:ENSPTRG00000015991
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 25

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	3	NC_072401.2 (39618347..39695892, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	4	NC_072402.1 (39618321..39695861, complement)

Chromosome 3 - NC_072401.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

D4S2821 (e-PCR)
- UniSTS:52763

SHGC-67924 (e-PCR)
- UniSTS:18746

SHGC-30256 (e-PCR)
- UniSTS:52560

D4S335 (e-PCR)
- UniSTS:27992

G34472 (e-PCR)
- UniSTS:9917

SHGC-67941 (e-PCR)
- UniSTS:16318

G67564 (e-PCR)
- UniSTS:207040

G62134 (e-PCR)
- UniSTS:139201

G67567 (e-PCR)
- UniSTS:207041

G67569 (e-PCR)
- UniSTS:207043

G67570 (e-PCR)
- UniSTS:207044

G67571 (e-PCR)
- UniSTS:207045

G67565 (e-PCR)
- UniSTS:207046

D4S2578E (e-PCR)
- UniSTS:150982

G67566 (e-PCR)
- UniSTS:207047

SHGC-51647 (e-PCR)
- UniSTS:69086

STS-Z22642 (e-PCR)
- UniSTS:80101

STS-L23320 (e-PCR)
- UniSTS:30696

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info	PubMed
enables DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables DNA clamp loader activity	IEA Inferred from Electronic Annotation more info	PubMed
enables DNA clamp unloader activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in DNA repair	IEA Inferred from Electronic Annotation more info	PubMed
involved_in DNA replication	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of DNA replication factor C complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: replication factor C subunit 1

Names: replication factor C (activator 1) 1, 145kDa; replication factor C large subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072401.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

39618347..39695892 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009447518.4 → XP_009445793.1 replication factor C subunit 1 isoform X2

See identical proteins and their annotated locations for XP_009445793.1

UniProtKB/TrEMBL

A0A2J8IZA9, K7BM03

Related

ENSPTRP00000089036.1

Conserved Domains (4) summary

smart00382
Location:647 → 777

AAA; ATPases associated with a variety of cellular activities

cd00027
Location:409 → 480

BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...

pfam00004
Location:647 → 775

AAA; ATPase family associated with various cellular activities (AAA)

pfam08519
Location:914 → 1067

RFC1; Replication factor RFC1 C terminal domain
XM_001140765.6 → XP_001140765.1 replication factor C subunit 1 isoform X1

UniProtKB/TrEMBL

A0A2J8IZ97

Conserved Domains (4) summary

smart00382
Location:648 → 778

AAA; ATPases associated with a variety of cellular activities

cd00027
Location:409 → 480

BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...

pfam00004
Location:648 → 776

AAA; ATPase family associated with various cellular activities (AAA)

pfam08519
Location:915 → 1068

RFC1; Replication factor RFC1 C terminal domain
XM_054682837.2 → XP_054538812.1 replication factor C subunit 1 isoform X4
XM_054682836.2 → XP_054538811.1 replication factor C subunit 1 isoform X3