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ITGA2 integrin subunit alpha 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 471550, updated on 29-Mar-2024

Summary

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Official Symbol
ITGA2provided by VGNC
Official Full Name
integrin subunit alpha 2provided by VGNC
Primary source
VGNC:VGNC:4054
Locus tag
CK820_G0040525
See related
Ensembl:ENSPTRG00000016860
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See ITGA2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
32
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 4 NC_072402.2 (61545870..61671874, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 5 NC_072403.1 (61976214..62100461, complement)

Chromosome 4 - NC_072402.2Genomic Context describing neighboring genes Neighboring gene transcription factor NF-E4-like Neighboring gene large ribosomal subunit protein uL13-like Neighboring gene molybdenum cofactor synthesis 2 Neighboring gene uncharacterized LOC104006453 Neighboring gene integrin subunit alpha 1 Neighboring gene pelota mRNA surveillance and ribosome rescue factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
integrin alpha-2
Names
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    61545870..61671874 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016953318.4 → XP_016808807.1  integrin alpha-2 isoform X2

    UniProtKB/TrEMBL
    A0A2I3T1C0

  2. XM_526928.8 → XP_526928.2  integrin alpha-2 isoform X1

    See identical proteins and their annotated locations for XP_526928.2

    UniProtKB/TrEMBL
    A0A2I3T1C0, A0A2J8K979, A0A6D2VXU9, H2QQV6
    Related
    ENSPTRP00000028886.4
    Conserved Domains (3) summary
    smart00191
    Location:551 → 604
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:173 → 353
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:655 → 1060
    Integrin_alpha2; Integrin alpha

  3. XM_009449170.5 → XP_009447445.1  integrin alpha-2 isoform X3

    UniProtKB/TrEMBL
    A0A2I3T1C0
    Conserved Domains (3) summary
    smart00191
    Location:549 → 602
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:171 → 351
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:653 → 1058
    Integrin_alpha2; Integrin alpha

  4. XM_016953319.4 → XP_016808808.1  integrin alpha-2 isoform X4

    UniProtKB/TrEMBL
    A0A2J8K911, A0A2J8K970
    Related
    ENSPTRP00000071955.1
    Conserved Domains (3) summary
    smart00191
    Location:551 → 604
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:173 → 353
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:655 → 941
    Integrin_alpha2; Integrin alpha
Nucleotide Protein
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