FZD3 frizzled class receptor 3 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: FZD3provided by VGNC
Official Full Name: frizzled class receptor 3provided by VGNC
Primary source: VGNC:VGNC:868
Locus tag: CK820_G0013275
See related: Ensembl:ENSPTRG00000020122
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	7	NC_072405.2 (36850745..36927084)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	8	NC_072406.1 (40425857..40505858)

Chromosome 7 - NC_072405.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

RH122525 (e-PCR)
- UniSTS:138527

D7S3207 (e-PCR)
- UniSTS:229489

SGC31127 (e-PCR)
- UniSTS:15738

RH15824 (e-PCR)
- UniSTS:18846

D22S296 (e-PCR)
- UniSTS:147641

RH12433 (e-PCR)
- UniSTS:64961

A007B14 (e-PCR)
- UniSTS:28870

STS-AA024552 (e-PCR)
- UniSTS:46050

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables Wnt receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables Wnt-protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in canonical Wnt signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in non-canonical Wnt signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: frizzled-3

Names: frizzled 3, seven transmembrane spanning receptor; frizzled family receptor 3; frizzled homolog 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072405.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

36850745..36927084

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_528098.8 → XP_528098.1 frizzled-3 isoform X1

See identical proteins and their annotated locations for XP_528098.1

UniProtKB/TrEMBL

A0A2J8N8E6, A0A6D2Y4J0, H2QVZ0

Conserved Domains (2) summary

cd07449
Location:24 → 150

CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor

cd15033
Location:192 → 512

7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors
XM_001166266.7 → XP_001166266.2 frizzled-3 isoform X1

See identical proteins and their annotated locations for XP_001166266.2

UniProtKB/TrEMBL

A0A2J8N8E6, A0A6D2Y4J0, H2QVZ0

Conserved Domains (2) summary

cd07449
Location:24 → 150

CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor

cd15033
Location:192 → 512

7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors
XM_063816261.1 → XP_063672331.1 frizzled-3 isoform X2
XM_054657311.2 → XP_054513286.1 frizzled-3 isoform X3
XM_054657313.2 → XP_054513288.1 frizzled-3 isoform X4
XM_054657315.2 → XP_054513290.1 frizzled-3 isoform X4
XM_054657316.2 → XP_054513291.1 frizzled-3 isoform X4