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PAH phenylalanine hydroxylase [ Canis lupus familiaris (dog) ]

Gene ID: 475446, updated on 5-Mar-2024

Summary

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Official Symbol
PAHprovided by VGNC
Official Full Name
phenylalanine hydroxylaseprovided by VGNC
Primary source
VGNC:VGNC:54218
See related
Ensembl:ENSCAFG00845009553
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 15
Exon count:
13
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 15 NC_051819.1 (42245356..42325951, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 15 NC_006597.4 (41957869..42038236, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 15 NC_049236.1 (41882259..41962824, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 15 NC_049275.1 (41514955..41595406, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 15 NC_049756.1 (41612701..41693246, complement)

Chromosome 15 - NC_051819.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111090067 Neighboring gene insulin like growth factor 1 Neighboring gene uncharacterized LOC119869366 Neighboring gene uncharacterized LOC119869373 Neighboring gene achaete-scute family bHLH transcription factor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phenylalanine 4-monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-phenylalanine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tyrosine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phenylalanine-4-hydroxylase
XP_038352393.1
XP_038414790.1
XP_038478712.1
XP_038544383.1
XP_532671.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051819.1 Reference ROS_Cfam_1.0

    Range
    42245356..42325951 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038688455.1 → XP_038544383.1  phenylalanine-4-hydroxylase

    UniProtKB/TrEMBL
    A0A8C0LPC7
    Related
    ENSCAFP00845013087.1, ENSCAFT00845016828.1
    Conserved Domains (1) summary
    TIGR01268
    Location:19 → 451
    Phe4hydrox_tetr; phenylalanine-4-hydroxylase, tetrameric form

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049275.1 Alternate UMICH_Zoey_3.1

    Range
    41514955..41595406 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038496465.1 → XP_038352393.1  phenylalanine-4-hydroxylase

    Conserved Domains (1) summary
    TIGR01268
    Location:19 → 451
    Phe4hydrox_tetr; phenylalanine-4-hydroxylase, tetrameric form

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049756.1 Alternate UNSW_CanFamBas_1.0

    Range
    41612701..41693246 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038622784.1 → XP_038478712.1  phenylalanine-4-hydroxylase

    Conserved Domains (1) summary
    TIGR01268
    Location:19 → 451
    Phe4hydrox_tetr; phenylalanine-4-hydroxylase, tetrameric form

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049236.1 Alternate UU_Cfam_GSD_1.0

    Range
    41882259..41962824 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038558862.1 → XP_038414790.1  phenylalanine-4-hydroxylase

    UniProtKB/TrEMBL
    A0A8C0LPC7
    Conserved Domains (1) summary
    TIGR01268
    Location:19 → 451
    Phe4hydrox_tetr; phenylalanine-4-hydroxylase, tetrameric form

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    41957869..42038236 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_532671.7 → XP_532671.3  phenylalanine-4-hydroxylase

    UniProtKB/TrEMBL
    A0A8C0LPC7
    Conserved Domains (1) summary
    TIGR01268
    Location:19 → 451
    Phe4hydrox_tetr; phenylalanine-4-hydroxylase, tetrameric form
Nucleotide Protein
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