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ndufa2 NADH:ubiquinone oxidoreductase subunit A2 [ Danio rerio (zebrafish) ]

Gene ID: 554125, updated on 27-Mar-2024

Summary

Official Symbol
ndufa2provided by ZNC
Official Full Name
NADH:ubiquinone oxidoreductase subunit A2provided by ZNC
Primary source
ZFIN:ZDB-GENE-050522-377
See related
Ensembl:ENSDARG00000021984 AllianceGenome:ZFIN:ZDB-GENE-050522-377
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:112340
Summary
Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Is expressed in several structures, including alar plate midbrain region; intestinal bulb; musculature system; optic tectum; and optic vesicle. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 13. Orthologous to human NDUFA2 (NADH:ubiquinone oxidoreductase subunit A2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 21
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (44005518..44009169, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (44010352..44014003, complement)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene caudal type homeobox 1 b Neighboring gene synaptotagmin-1-like Neighboring gene arylsulfatase family, member Ib Neighboring gene uncharacterized LOC108180789 Neighboring gene IK cytokine Neighboring gene arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
part_of mitochondrial respiratory chain complex I IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
located_in respirasome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
Names
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2
NP_001019591.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024420.1NP_001019591.1  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

    See identical proteins and their annotated locations for NP_001019591.1

    Status: PROVISIONAL

    Source sequence(s)
    BC095772
    UniProtKB/TrEMBL
    B2GSD8, Q4VBI5
    Related
    ENSDARP00000031098.4, ENSDART00000028960.6
    Conserved Domains (1) summary
    smart00916
    Location:3099
    L51_S25_CI-B8; Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    44005518..44009169 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)