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MAPK12 mitogen-activated protein kinase 12 [ Canis lupus familiaris (dog) ]

Gene ID: 607023, updated on 5-Mar-2024

Summary

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Official Symbol
MAPK12provided by VGNC
Official Full Name
mitogen-activated protein kinase 12provided by VGNC
Primary source
VGNC:VGNC:42993
See related
Ensembl:ENSCAFG00845005996
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
13
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (17713650..17721939)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (16964857..16973137)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (17893208..17901489)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (17437731..17446013)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (17761009..17769279)

Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene plexin B2 Neighboring gene mitogen-activated protein kinase 11 Neighboring gene histone deacetylase 10 Neighboring gene tubulin gamma complex component 6 Neighboring gene selenoprotein O

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables MAP kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mitogen-activated protein kinase 12
XP_038344159.1
XP_038344160.1
XP_038344161.1
XP_038344162.1
XP_038344163.1
XP_038344164.1
XP_038406058.1
XP_038406059.1
XP_038406060.1
XP_038406061.1
XP_038406062.1
XP_038406063.1
XP_038470045.1
XP_038470046.1
XP_038470047.1
XP_038470048.1
XP_038470049.1
XP_038470050.1
XP_038491608.1
XP_038491617.1
XP_038491624.1
XP_038491636.1
XP_038491645.1
XP_038535395.1
XP_038535396.1
XP_038535397.1
XP_038535398.1
XP_038535399.1
XP_038535400.1
XP_848658.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051814.1 Reference ROS_Cfam_1.0

    Range
    17713650..17721939
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038679472.1 → XP_038535400.1  mitogen-activated protein kinase 12 isoform X4

    Conserved Domains (1) summary
    cl21453
    Location:1 → 285
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038679469.1 → XP_038535397.1  mitogen-activated protein kinase 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QXC7, A0A8C0SV89, A0A8I3N1Y2
    Conserved Domains (1) summary
    cd07880
    Location:11 → 365
    STKc_p38gamma; Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase (also called MAPK12)

  3. XM_038679471.1 → XP_038535399.1  mitogen-activated protein kinase 12 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QXC7, A0A8C0SV89, A0A8I3N1Y2
    Conserved Domains (1) summary
    cl21453
    Location:11 → 340
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038679467.1 → XP_038535395.1  mitogen-activated protein kinase 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QXC7, A0A8C0SV89, A0A8I3N1Y2
    Conserved Domains (1) summary
    cd07880
    Location:11 → 365
    STKc_p38gamma; Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase (also called MAPK12)

  5. XM_038679468.1 → XP_038535396.1  mitogen-activated protein kinase 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QXC7, A0A8C0SV89, A0A8I3N1Y2
    Related
    ENSCAFP00845008461.1, ENSCAFT00845010840.1
    Conserved Domains (1) summary
    cd07880
    Location:11 → 365
    STKc_p38gamma; Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase (also called MAPK12)

  6. XM_038679470.1 → XP_038535398.1  mitogen-activated protein kinase 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C0N1E4, A0A8C0QXC7, A0A8C0SV89, A0A8I3N1Y2, A0A8I3ND88
    Related
    ENSCAFP00845008421.1, ENSCAFT00845010789.1
    Conserved Domains (1) summary
    cd07880
    Location:11 → 353
    STKc_p38gamma; Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase (also called MAPK12)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049270.1 Alternate UMICH_Zoey_3.1

    Range
    17437731..17446013
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038488236.1 → XP_038344164.1  mitogen-activated protein kinase 12 isoform X4

    Conserved Domains (1) summary
    cl21453
    Location:1 → 285
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038488233.1 → XP_038344161.1  mitogen-activated protein kinase 12 isoform X1

    Conserved Domains (1) summary
    cd07880
    Location:11 → 365
    STKc_p38gamma; Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase (also called MAPK12)

  3. XM_038488235.1 → XP_038344163.1  mitogen-activated protein kinase 12 isoform X3

    Conserved Domains (1) summary
    cl21453
    Location:11 → 340
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038488231.1 → XP_038344159.1  mitogen-activated protein kinase 12 isoform X1

    Conserved Domains (1) summary
    cd07880
    Location:11 → 365
    STKc_p38gamma; Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase (also called MAPK12)

  5. XM_038488232.1 → XP_038344160.1  mitogen-activated protein kinase 12 isoform X1

    Conserved Domains (1) summary
    cd07880
    Location:11 → 365
    STKc_p38gamma; Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase (also called MAPK12)

  6. XM_038488234.1 → XP_038344162.1  mitogen-activated protein kinase 12 isoform X2

    Conserved Domains (1) summary
    cd07880
    Location:11 → 353
    STKc_p38gamma; Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase (also called MAPK12)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

    Range
    17761009..17769279
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038614122.1 → XP_038470050.1  mitogen-activated protein kinase 12 isoform X4

    Conserved Domains (1) summary
    cl21453
    Location:1 → 285
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038614119.1 → XP_038470047.1  mitogen-activated protein kinase 12 isoform X1

    Conserved Domains (1) summary
    cd07880
    Location:11 → 365
    STKc_p38gamma; Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase (also called MAPK12)

  3. XM_038614118.1 → XP_038470046.1  mitogen-activated protein kinase 12 isoform X1

    Conserved Domains (1) summary
    cd07880
    Location:11 → 365
    STKc_p38gamma; Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase (also called MAPK12)

  4. XM_038614121.1 → XP_038470049.1  mitogen-activated protein kinase 12 isoform X3

    Conserved Domains (1) summary
    cl21453
    Location:11 → 340
    PKc_like; Protein Kinases, catalytic domain

  5. XM_038614117.1 → XP_038470045.1  mitogen-activated protein kinase 12 isoform X1

    Conserved Domains (1) summary
    cd07880
    Location:11 → 365
    STKc_p38gamma; Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase (also called MAPK12)

  6. XM_038614120.1 → XP_038470048.1  mitogen-activated protein kinase 12 isoform X2

    Conserved Domains (1) summary
    cd07880
    Location:11 → 353
    STKc_p38gamma; Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase (also called MAPK12)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

    Range
    17893208..17901489
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038550135.1 → XP_038406063.1  mitogen-activated protein kinase 12 isoform X4

    Conserved Domains (1) summary
    cl21453
    Location:1 → 285
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038550132.1 → XP_038406060.1  mitogen-activated protein kinase 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QXC7, A0A8C0SV89, A0A8I3N1Y2
    Conserved Domains (1) summary
    cd07880
    Location:11 → 365
    STKc_p38gamma; Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase (also called MAPK12)

  3. XM_038550131.1 → XP_038406059.1  mitogen-activated protein kinase 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QXC7, A0A8C0SV89, A0A8I3N1Y2
    Conserved Domains (1) summary
    cd07880
    Location:11 → 365
    STKc_p38gamma; Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase (also called MAPK12)

  4. XM_038550134.1 → XP_038406062.1  mitogen-activated protein kinase 12 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QXC7, A0A8C0SV89, A0A8I3N1Y2
    Conserved Domains (1) summary
    cl21453
    Location:11 → 340
    PKc_like; Protein Kinases, catalytic domain

  5. XM_038550130.1 → XP_038406058.1  mitogen-activated protein kinase 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QXC7, A0A8C0SV89, A0A8I3N1Y2
    Conserved Domains (1) summary
    cd07880
    Location:11 → 365
    STKc_p38gamma; Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase (also called MAPK12)

  6. XM_038550133.1 → XP_038406061.1  mitogen-activated protein kinase 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C0N1E4, A0A8C0QXC7, A0A8C0SV89, A0A8I3N1Y2, A0A8I3ND88
    Conserved Domains (1) summary
    cd07880
    Location:11 → 353
    STKc_p38gamma; Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase (also called MAPK12)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    16964857..16973137
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038635717.1 → XP_038491645.1  mitogen-activated protein kinase 12 isoform X4

    Conserved Domains (1) summary
    cl21453
    Location:1 → 285
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038635696.1 → XP_038491624.1  mitogen-activated protein kinase 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QXC7, A0A8C0SV89, A0A8I3N1Y2
    Conserved Domains (1) summary
    cd07880
    Location:11 → 365
    STKc_p38gamma; Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase (also called MAPK12)

  3. XM_038635708.1 → XP_038491636.1  mitogen-activated protein kinase 12 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QXC7, A0A8C0SV89, A0A8I3N1Y2
    Conserved Domains (1) summary
    cl21453
    Location:11 → 340
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038635680.1 → XP_038491608.1  mitogen-activated protein kinase 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QXC7, A0A8C0SV89, A0A8I3N1Y2
    Conserved Domains (1) summary
    cd07880
    Location:11 → 365
    STKc_p38gamma; Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase (also called MAPK12)

  5. XM_038635689.1 → XP_038491617.1  mitogen-activated protein kinase 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QXC7, A0A8C0SV89, A0A8I3N1Y2
    Conserved Domains (1) summary
    cd07880
    Location:11 → 365
    STKc_p38gamma; Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase (also called MAPK12)

  6. XM_843565.4 → XP_848658.3  mitogen-activated protein kinase 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C0N1E4, A0A8C0QXC7, A0A8C0SV89, A0A8I3N1Y2, A0A8I3ND88
    Conserved Domains (1) summary
    cd07880
    Location:11 → 353
    STKc_p38gamma; Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase (also called MAPK12)
Nucleotide Protein
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