JAG1 jagged canonical Notch ligand 1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: JAG1provided by VGNC
Official Full Name: jagged canonical Notch ligand 1provided by VGNC
Primary source: VGNC:VGNC:6177
Locus tag: CK820_G0017604
See related: Ensembl:ENSPTRG00000013250
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 26

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	21	NC_072419.2 (17148030..17186406, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	20	NC_072418.1 (17159319..17195574, complement)

Chromosome 21 - NC_072419.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

Z94359 (e-PCR)
- UniSTS:42767

Jag1 (e-PCR), detects polymorphism
- UniSTS:143636

SHGC-33818 (e-PCR)
- UniSTS:35895

RH123107 (e-PCR)
- UniSTS:135487

PMC111189P2 (e-PCR)
- UniSTS:270221

STS-T96855 (e-PCR)
- UniSTS:31379

JAG1_1238 (e-PCR)
- UniSTS:277396

JAG1_v358 (e-PCR)
- UniSTS:277396

WI-8071 (e-PCR)
- UniSTS:64191

WI-12707 (e-PCR)
- UniSTS:44738

WI-17032 (e-PCR)
- UniSTS:13027

D20S1091 (e-PCR)
- UniSTS:473578

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables Notch binding	IEA Inferred from Electronic Annotation more info	PubMed
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in Notch signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell communication	IEA Inferred from Electronic Annotation more info	PubMed
involved_in multicellular organism development	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: protein jagged-1

Names: jagged 1 (Alagille syndrome)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072419.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

17148030..17186406 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001169666.7 → XP_001169666.1 protein jagged-1

See identical proteins and their annotated locations for XP_001169666.1

UniProtKB/TrEMBL

A0A2I3T680, A0A2J8MSU0, A0A6D2WM77, H2QJZ0

Related

ENSPTRP00000022729.4

Conserved Domains (5) summary

smart00215
Location:863 → 930

VWC_out; von Willebrand factor (vWF) type C domain

cd00054
Location:629 → 665

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

pfam00008
Location:748 → 777

EGF; EGF-like domain

pfam01414
Location:167 → 229

DSL; Delta serrate ligand

pfam07657
Location:32 → 107

MNNL; N terminus of Notch ligand