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Ypel4 yippee-like 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 502643, updated on 4-Jan-2025

Summary

Official Symbol
Ypel4provided by RGD
Official Full Name
yippee-like 4provided by RGD
Primary source
RGD:1560142
See related
EnsemblRapid:ENSRNOG00000069900 AllianceGenome:RGD:1560142
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable metal ion binding activity. Predicted to act upstream of or within several processes, including negative regulation of erythrocyte clearance; negative regulation of erythrocyte differentiation; and protein localization to plasma membrane. Predicted to be located in nucleolus. Orthologous to human YPEL4 (yippee like 4). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Spleen (RPKM 184.9), Brain (RPKM 82.1) and 6 other tissues See more
Orthologs
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Genomic context

See Ypel4 in Genome Data Viewer
Location:
3q24
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (90222060..90227395)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (69815373..69820708)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (72134719..72139204)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene mediator complex subunit 19 Neighboring gene zinc finger DHHC-type palmitoyltransferase 5 Neighboring gene uncharacterized LOC120101590 Neighboring gene cleavage factor polyribonucleotide kinase subunit 1 Neighboring gene microRNA 130a Neighboring gene microRNA 3590 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding  
Component Evidence Code Pubs
located_in nucleolus  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024369.1NP_001019540.1  protein yippee-like 4

    See identical proteins and their annotated locations for NP_001019540.1

    Status: PROVISIONAL

    Source sequence(s)
    BC083749
    UniProtKB/Swiss-Prot
    Q5XID5
    UniProtKB/TrEMBL
    A0A8I6A1T5, A6HMR2
    Related
    ENSRNOP00000085506.1, ENSRNOT00000095945.2
    Conserved Domains (1) summary
    cl13152
    Location:28118
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    90222060..90227395
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039105727.2XP_038961655.1  protein yippee-like 4 isoform X1

    UniProtKB/Swiss-Prot
    Q5XID5
    UniProtKB/TrEMBL
    A0A8I6A1T5, A6HMR2
    Conserved Domains (1) summary
    cl13152
    Location:28118
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains
  2. XM_063284405.1XP_063140475.1  protein yippee-like 4 isoform X1

    UniProtKB/Swiss-Prot
    Q5XID5
    UniProtKB/TrEMBL
    A0A8I6A1T5, A6HMR2
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