Expression and cellular localization of the Toucan protein during Drosophila oogenesis

Mech Dev. 2000 Feb;90(2):289-92. doi: 10.1016/s0925-4773(99)00240-3.

Abstract

The toucan (toc) gene is required in the germline for somatic cell patterning during Drosophila oogenesis. To better understand the function of toc, we performed a detailed analysis of the distribution of the Toucan protein during oogenesis. Toc expression is restricted to the germline cells and shows a dynamic distribution pattern throughout follicle development. Mislocalization of the Toc protein in mutant follicles in which the microtubule network is altered indicates that microtubules play a role in Toc localization during oogenesis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies
  • Drosophila
  • Female
  • Gene Expression
  • Glutathione Transferase / metabolism
  • Insect Proteins / genetics
  • Insect Proteins / immunology
  • Insect Proteins / metabolism*
  • Microtubules / metabolism
  • Oocytes / metabolism
  • Oogenesis
  • Ovary
  • Rabbits
  • Recombinant Fusion Proteins / genetics
  • Recombinant Fusion Proteins / immunology
  • Recombinant Fusion Proteins / metabolism
  • Subcellular Fractions

Substances

  • Antibodies
  • Insect Proteins
  • Recombinant Fusion Proteins
  • Glutathione Transferase