Purpose: To describe two patients with unique lenticular nodular proliferations.
Design: Observational case reports.
Methods: The clinical histories and pathologic findings of two patients with lenticular nodular proliferations were reviewed.
Results: One patient with persistent hyperplastic primary vitreous and another patient with trauma developed lenticular nodular proliferations. The nodules were vascularized collections of foamy histiocytes, multinucleated cells, lens capsule, and lens epithelium that had undergone fibrous metaplasia. The lesions were classified as lenticular fibroxanthomatous nodules.
Conclusions: A lenticular fibroxanthomatous nodule is a unique clinicopathologic entity that should be differentiated from Soemmerring ring, Elschnig pearl, and other simulating entities such as juvenile xanthogranuloma.