Abstract
Hair and nails are skin appendages that share with other ectodermal tissues a common developmental pathway. Inherited disorders affecting these two structures therefore very often involve other epithelial components and present with multiple anomalies, generating both physical and psychological distress among patients and their families. The present review briefly describes major recent advances in our understanding of hair and nail genodermatoses.
MeSH terms
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Ectodermal Dysplasia / epidemiology
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Ectodermal Dysplasia / genetics
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Ectodermal Dysplasia / therapy
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Female
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Gene Expression Regulation, Developmental
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Genetic Predisposition to Disease / epidemiology*
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Hair Diseases / epidemiology
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Hair Diseases / genetics*
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Hair Diseases / therapy
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Humans
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Hypotrichosis / epidemiology
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Hypotrichosis / genetics
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Hypotrichosis / therapy
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Incidence
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Male
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Nail Diseases / epidemiology
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Nail Diseases / genetics*
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Nail Diseases / therapy
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Nail-Patella Syndrome / epidemiology
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Nail-Patella Syndrome / genetics
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Nail-Patella Syndrome / therapy
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Prognosis
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Risk Assessment
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Skin Diseases, Genetic / diagnosis
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Skin Diseases, Genetic / epidemiology