The undescended testis

Indian J Pediatr. 2005 May;72(5):429-32. doi: 10.1007/BF02731742.

Abstract

Testicular development is determined by the influence of the SRY gene on the Y chromosome of the fetus. This influences the germ cells to produce testosterone and Mullerian inhibiting substance which control descent of the testis. Maldescent of the testis occurs in 0.8% of boys. Current best advice is to perform orchidopexy before the age of two years, therefore a programme for examination by skilled healthcare workers should be established in the first year of life. Indications for surgery include a possible beneficial effect on fertility, malignant potential particularly if intra-abdominal, torsion or trauma and social considerations. Hormonal treatment in the first three months of life is recommended by some. Laparoscopy is the optimum method for evaluating and managing the intra-abdominal testis.

Publication types

  • Review

MeSH terms

  • Cryptorchidism / diagnosis*
  • Cryptorchidism / physiopathology
  • Cryptorchidism / therapy*
  • Diagnosis, Differential
  • Gonadotropins / therapeutic use
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Testicular Diseases / diagnosis
  • Urologic Surgical Procedures, Male / methods

Substances

  • Gonadotropins