Abstract
Urinary tract infections can be a significant source of morbidity in the pediatric population. The mainstay of evaluating urinary tract infections in children has been physical examination, urinalysis and culture, and renal and bladder sonography and contrast cystography. However, novel clinical paradigms now consider the importance of various risk factors, such as bacterial virulence and antibiotic-resistance patterns, elimination disorders, and the role of innate immunity and inflammation in determining the likelihood of renal cortical scarring.
MeSH terms
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Animals
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Anti-Bacterial Agents / therapeutic use
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Bacteria / pathogenicity
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Bacterial Infections / complications*
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Bacterial Infections / diagnosis*
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Bacterial Infections / drug therapy
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Bacterial Infections / immunology
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Child
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Cicatrix / etiology*
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Cicatrix / microbiology
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Drug Resistance, Microbial
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Humans
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Immunity, Innate
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Inflammation / microbiology
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Kidney Cortex
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Kidney Diseases / etiology*
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Kidney Diseases / microbiology
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Risk Factors
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Urinary Tract Infections / complications*
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Urinary Tract Infections / diagnosis*
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Urinary Tract Infections / drug therapy
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Urinary Tract Infections / immunology
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Vesico-Ureteral Reflux / complications
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Virulence