Maternal and neonatal vitamin B12 deficiency detected through expanded newborn screening--United States, 2003-2007

Cynthia F Hinton; Jelili A Ojodu; Paul M Fernhoff; Sonja A Rasmussen; Kelley S Scanlon; W Harry Hannon

doi:10.1016/j.jpeds.2010.03.006

Maternal and neonatal vitamin B12 deficiency detected through expanded newborn screening--United States, 2003-2007

J Pediatr. 2010 Jul;157(1):162-3. doi: 10.1016/j.jpeds.2010.03.006. Epub 2010 Apr 18.

Authors

Cynthia F Hinton¹, Jelili A Ojodu, Paul M Fernhoff, Sonja A Rasmussen, Kelley S Scanlon, W Harry Hannon

Affiliation

¹ National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. ceh9@cdc.gov

PMID: 20400092
DOI: 10.1016/j.jpeds.2010.03.006

Abstract

The incidence of neonatal vitamin B12 (cobalamin) deficiency because of maternal deficiency was determined by surveying state newborn screening programs. Thirty-two infants with nutritional vitamin B12 deficiency were identified (0.88/100,000 newborns). Pregnant women should be assessed for their risk of inadequate intake/malabsorption of vitamin B12.

MeSH terms

Adult
Female
Humans
Infant, Newborn
Male
Maternal Nutritional Physiological Phenomena
Maternal-Fetal Exchange
Mothers*
Neonatal Screening / methods*
Pregnancy
Pregnancy Complications / epidemiology
Risk Factors
Surveys and Questionnaires
United States / epidemiology
Vitamin B 12 Deficiency / diagnosis*
Vitamin B 12 Deficiency / epidemiology*
Vitamin B 12 Deficiency / etiology