Pediatric vasculitis

Pediatr Clin North Am. 2012 Apr;59(2):407-23. doi: 10.1016/j.pcl.2012.03.013. Epub 2012 Apr 6.

Abstract

Childhood vasculitis is a challenging and complex group of conditions that are multisystem in nature and often require integrated care from multiple subspecialties, including rheumatology, dermatology, cardiology, nephrology, neurology, and gastroenterology. Vasculitis is defined as the presence of inflammation in the blood vessel wall. The site of vessel involvement, size of the affected vessels, extent of vascular injury, and underlying pathology determine the disease phenotype and severity. This article explores the classification and general features of pediatric vasculitis, as well as the clinical presentation, diagnostic evaluation, and therapeutic options for the most common vasculitides.

Publication types

  • Review

MeSH terms

  • Analgesics / therapeutic use
  • Anti-Inflammatory Agents / therapeutic use
  • Child
  • Humans
  • IgA Vasculitis / diagnosis
  • IgA Vasculitis / epidemiology
  • IgA Vasculitis / etiology
  • IgA Vasculitis / therapy
  • Immunoglobulins, Intravenous / therapeutic use
  • Immunologic Factors / therapeutic use
  • Mucocutaneous Lymph Node Syndrome / diagnosis
  • Mucocutaneous Lymph Node Syndrome / drug therapy
  • Mucocutaneous Lymph Node Syndrome / epidemiology
  • Mucocutaneous Lymph Node Syndrome / etiology
  • Plasmapheresis
  • Polyarteritis Nodosa / diagnosis
  • Polyarteritis Nodosa / drug therapy
  • Takayasu Arteritis / diagnosis
  • Takayasu Arteritis / drug therapy
  • Vasculitis* / diagnosis
  • Vasculitis* / epidemiology
  • Vasculitis* / etiology
  • Vasculitis* / therapy
  • Vasculitis, Central Nervous System / diagnosis
  • Vasculitis, Central Nervous System / drug therapy

Substances

  • Analgesics
  • Anti-Inflammatory Agents
  • Immunoglobulins, Intravenous
  • Immunologic Factors