Favourable anatomy after end-to-side repair of interrupted aortic arch

Heart Lung Circ. 2014 Mar;23(3):256-64. doi: 10.1016/j.hlc.2013.08.006. Epub 2013 Aug 30.

Abstract

Objective: To evaluate cardiovascular outcomes in patients with aortic arch repair and their possible correlation with arch geometry.

Methods: Ten patients who underwent end-to-side repair for aortic arch interruption (IAA), older than 10 years were compared to a cohort of 10 post coarctation (CoA) repair patients matched for age, sex and age at repair. Mean age at operation was 9.7±6.5 days. Patients underwent a resting and 24 h blood pressure measurements, exercise study, MRI, transthoracic echocardiography and vascular studies.

Results: Seven patients developed hypertension, two from IAA group and five from CoA group. Nine patients (45%) had gothic arch geometry, three from IAA group and six from CoA group. Despite differences in arch geometry, both groups had normal LV mass, LV function and vascular function.

Conclusion: No differences in functional or morphologic outcomes could be demonstrated between the end-to-side repair of the arch by sternotomy and the conventional coarctation repair by thoracotomy. A favourable arch geometry can be achieved after the end-to-side repair of the aortic arch. In the present study, we could not correlate adverse arch geometry with any adverse cardio-vascular outcomes. After neonatal arch repair, the contributive role of aortic arch geometry to late hypertension remains uncertain.

Keywords: Aortic arch; Aortic coarctation; Comparative studies; Congenital heart disease; Hypertension; Interrupted aortic arch.

Publication types

  • Clinical Trial
  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Aorta, Thoracic / abnormalities*
  • Aorta, Thoracic / pathology*
  • Aorta, Thoracic / physiopathology
  • Aorta, Thoracic / surgery*
  • Blood Pressure
  • Child
  • Child, Preschool
  • Female
  • Follow-Up Studies
  • Heart Defects, Congenital / pathology*
  • Heart Defects, Congenital / physiopathology
  • Heart Defects, Congenital / surgery*
  • Humans
  • Hypertension / etiology
  • Hypertension / physiopathology
  • Male
  • Retrospective Studies