Is Tumor of Follicular Infundibulum a Reaction to Dermal Scarring?

Am J Dermatopathol. 2015 Jul;37(7):535-8. doi: 10.1097/DAD.0000000000000130.

Abstract

Tumor of follicular infundibulum (TFI) is currently believed to be a benign epithelial neoplasm with follicular differentiation. It has been suggested that TFI is associated with dermal scarring, but further investigation is needed to confirm this correlation. To approach this question, a retrospective study was presented, a total of 67 cases (64 lesions) were found in a search covering cases over a 10-year period. Overall, the presence of histological dermal scarring was noted in 34 of 64 (53.13%) cases. Of the cases where TFI was an incidental finding, the presence of dermal scarring was noted in 13 of 18 (72.22%) cases. Meanwhile, of the cases where TFI was the main diagnosis, the presence of dermal scarring was noted in 12 of 34 (35.29%) cases. This suggests that TFI may, in some cases, represent an epidermal reaction pattern to dermal scarring.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cicatrix / complications
  • Cicatrix / pathology*
  • Female
  • Hair Follicle*
  • Humans
  • Incidental Findings
  • Male
  • Middle Aged
  • Neoplasms, Adnexal and Skin Appendage / complications
  • Neoplasms, Adnexal and Skin Appendage / pathology*
  • Neoplasms, Multiple Primary / pathology*
  • Retrospective Studies
  • Skin Neoplasms / complications
  • Skin Neoplasms / pathology*