Indications and Outcomes of Osteoporosis and Bone Modulation Therapies

Oral Maxillofac Surg Clin North Am. 2015 Nov;27(4):567-71. doi: 10.1016/j.coms.2015.06.009. Epub 2015 Sep 9.

Abstract

Osteoporosis is a disorder of bone strength that leads to an increased risk of fractures. It is most commonly seen in patients aged 50 or older, although it can sometimes occur at a younger age if there are other comorbidities present. The most common cause of osteoporosis by far is menopause, although it also occurs in men, usually with higher morbidity rates than those seen in women. There are many treatment options available, such as anabolics and antiresorptives, with many more currently being developed. However, osteoporosis remains grossly unrecognized and untreated, resulting in a significant strain on the American economy.

Keywords: Anabolics; Bisphosphonates; Bone mineral density; FRAX; Fracture; Glucocorticoids; Osteoporosis.

Publication types

  • Review

MeSH terms

  • Bone Density Conservation Agents / therapeutic use*
  • Female
  • Fractures, Bone / epidemiology
  • Fractures, Bone / etiology
  • Fractures, Bone / prevention & control*
  • Humans
  • Incidence
  • Male
  • Osteoporosis / complications
  • Osteoporosis / drug therapy*
  • Osteoporosis / epidemiology
  • Osteoporosis / etiology
  • Risk Factors
  • United States / epidemiology

Substances

  • Bone Density Conservation Agents