Anal Dysplasia

Craig A Messick; Miguel A Rodriguez-Bigas

doi:10.1016/j.soc.2016.07.005

Anal Dysplasia

Surg Oncol Clin N Am. 2017 Jan;26(1):33-43. doi: 10.1016/j.soc.2016.07.005.

Authors

Craig A Messick¹, Miguel A Rodriguez-Bigas²

Affiliations

¹ Section of Colon and Rectal Surgery, Surgical Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA. Electronic address: Cmessick@mdanderson.org.
² Section of Colon and Rectal Surgery, Surgical Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.

PMID: 27889035
DOI: 10.1016/j.soc.2016.07.005

Abstract

Anal dysplasia is a cytopathology term describing specific squamous cell morphology and represents a varying degree of benign changes. Often a source of confusion, the current iteration includes two types, low-grade and high-grade, and carries significant clinical implications. This article updates readers on the current definition of anal dysplasia, describes its incidence and prevalence, defines high-risk populations, and highlights diagnostics, treatment, and long-term management strategies for patients with anal dysplasia.

Keywords: Anal cytology; Anal dysplasia; HGAIN; HSIL; High-resolution anoscopy; LGAIN; LSIL; Squamous cell carcinoma.

Publication types

Review

MeSH terms

Anus Neoplasms / epidemiology
Anus Neoplasms / pathology*
Carcinoma in Situ / epidemiology
Carcinoma in Situ / pathology*
Humans
Incidence
Prevalence