Congenital and Acquired Valvular Heart Disease in Pregnancy

Curr Cardiol Rep. 2017 Aug 24;19(10):96. doi: 10.1007/s11886-017-0910-6.

Abstract

Purpose of review: The number of pregnancies complicated by valvular heart disease is increasing. This review describes the hemodynamic effects of clinically important valvular abnormalities during pregnancy and reviews current guideline-driven management strategies.

Recent findings: Valvular heart disease in women of childbearing age is most commonly caused by congenital abnormalities and rheumatic heart disease. Regurgitant lesions are well tolerated, while stenotic lesions are associated with a higher risk of pregnancy-related complications. Management of symptomatic disease during pregnancy is primarily medical, with percutaneous interventions considered for refractory symptoms. Most guidelines addressing the management of valvular heart disease during pregnancy are based on case reports and observational studies. Additional investigation is required to further advance the care of this growing patient population.

Keywords: Congenital heart disease; Pregnancy; Rheumatic heart disease; Structural heart disease; Valvular heart disease.

Publication types

  • Review

MeSH terms

  • Female
  • Heart Defects, Congenital
  • Heart Valve Diseases / congenital
  • Heart Valve Diseases / etiology*
  • Heart Valve Diseases / therapy
  • Hemodynamics
  • Humans
  • Pregnancy
  • Pregnancy Complications, Cardiovascular / etiology*
  • Pregnancy Complications, Cardiovascular / therapy
  • Rheumatic Heart Disease / complications*