PET/Computed Tomography and Precision Medicine: Gastric Cancer

PET Clin. 2017 Oct;12(4):437-447. doi: 10.1016/j.cpet.2017.05.004. Epub 2017 Jul 15.

Abstract

Gastric cancer is a disease with low survival rates and high morbidity, requiring accurate and prompt diagnosis and treatment. Although limited in the evaluation of the primary tumor as such, the metabolic information of primary tumors in an 18F-FDG PET/CT study can assist in surgical and treatment planning and differentiating gastric cancers. It detects nodal disease with good specificity and positive predictive value, thus enabling appropriate therapy for individual patients. It provides valuable information about distant metastases, altering therapy decisions. It has reasonably good performance in detecting recurrent disease and in the follow-up of patients.

Keywords: Gastric cancer; Gastric carcinoma; Gastric lymphoma; PET; PET/CT.

Publication types

  • Review

MeSH terms

  • Fluorodeoxyglucose F18
  • Humans
  • Positron Emission Tomography Computed Tomography*
  • Precision Medicine*
  • Radiopharmaceuticals
  • Sensitivity and Specificity
  • Stomach Neoplasms / diagnostic imaging*
  • Stomach Neoplasms / therapy

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18