High-intensity focused ultrasound therapy

Best Pract Res Clin Obstet Gynaecol. 2018 Jan:46:74-83. doi: 10.1016/j.bpobgyn.2017.09.002. Epub 2017 Oct 3.

Abstract

High-intensity focused ultrasound therapy has received increasing interest in the management of benign uterine tumors. Either magnetic resonance or ultrasound imaging has been used to target and monitor the ablation process. This article provides an overview of the background, clinical use, treatment outcomes, and safety of high-intensity focused ultrasound in the treatment of uterine fibroids and adenomyosis, including a summary of clinical trials comparing magnetic resonance- or ultrasound-guided high-intensity focused ultrasound with other minimally invasive or surgical interventions. The potential of this treatment modality as an alternative uterus-sparing option for women with fibroids and adenomyosis is discussed.

Keywords: Adenomyosis; Fibroid; High-intensity focused ultrasound; Magnetic resonance-guided; Ultrasound-guided.

Publication types

  • Review

MeSH terms

  • Adenomyosis / diagnostic imaging
  • Adenomyosis / surgery*
  • Female
  • High-Intensity Focused Ultrasound Ablation / adverse effects
  • High-Intensity Focused Ultrasound Ablation / methods*
  • Humans
  • Leiomyoma / diagnostic imaging
  • Leiomyoma / surgery*
  • Magnetic Resonance Imaging
  • Organ Sparing Treatments
  • Patient Selection
  • Pregnancy
  • Prospective Studies
  • Randomized Controlled Trials as Topic
  • Treatment Outcome
  • Uterine Neoplasms / diagnostic imaging
  • Uterine Neoplasms / surgery*
  • Uterus / surgery