Prognosis of Hepatic Encephalopathy

Clin Liver Dis. 2020 May;24(2):219-229. doi: 10.1016/j.cld.2020.01.004. Epub 2020 Mar 2.

Abstract

The presence of hepatic encephalopathy is often associated with worse clinical outcomes and increased mortality. Even subclinical hepatic encephalopathy has clinical impacts on daily life and has been linked to increased falls, motor vehicle accidents, and hospitalizations. The presence and degree of hepatic encephalopathy can also affect survival outcomes in cirrhosis, acute liver failure, and liver transplant recipients. Patients may have improved clinical outcomes after treatment of hepatic encephalopathy, but the long-term impact of treatment on prognosis is unclear.

Keywords: Decompensation; Encephalopathy; Hospitalization; Prognosis; Survival.

Publication types

  • Review

MeSH terms

  • Asymptomatic Diseases
  • Hepatic Encephalopathy* / drug therapy
  • Hepatic Encephalopathy* / etiology
  • Humans
  • Liver Cirrhosis* / complications
  • Liver Cirrhosis* / physiopathology
  • Liver Cirrhosis* / surgery
  • Liver Transplantation / adverse effects
  • Postoperative Period
  • Preoperative Period
  • Prognosis
  • Risk Factors
  • Survival Rate