During morphogenesis, changes in the shapes of individual cells are harnessed to mold an entire tissue. These changes in cell shapes require the coupled remodeling of the plasma membrane and underlying actin cytoskeleton. In this review, we highlight cellularization of the Drosophila embryo as a model system to uncover principles of how membrane and actin dynamics are co-regulated in space and time to drive morphogenesis.
Keywords: Actin; Cortical compartments; Cytokinesis; Endocytosis; Exocytosis; Membrane reservoir; Membrane trafficking; Myosin-2; Phosphoinositides.
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