Sudden respiratory and circulatory collapse after cesarean section: Amniotic fluid embolism or other reasons? - a case report

BMC Pregnancy Childbirth. 2022 Apr 28;22(1):369. doi: 10.1186/s12884-022-04701-3.

Abstract

Background: For a healthy parturient, a cardiopulmonary collapse that suddenly occurs shortly after an uneventful caesarean section is a relatively rare event and presents a significant challenge for the anesthesia provider.

Case presentation: Amniotic fluid embolism (AFE) is characterized by acute and rapid collapse and is well known to the obstetric team. Our patient experienced sudden cardiovascular collapse, severe respiratory difficulty and hypoxia, in the absence of other explanations for these findings at the time, and thus AFE was immediately become the focus of the consideration. However, there is no quick, standard laboratory test for AFE, therefore the diagnosis is one of exclusion based on presenting symptoms and clinical course. After given symptomatic treatment, the patient made an uneventful initial recovery in a short period and developed a rash. We recognized that the postpartum shock was associated with delayed anaphylaxis of antibiotics.

Conclusions: These observations have implications for understanding whenever administering drugs in surgery, which may affect the anesthesiologist's judgment regarding the complications of anesthesia. Even though serious complications of common perioperative drugs may rarely occur, anesthesia providers should be aware of the consideration. Early recognition and effective treatment are more important than prompt diagnosis.

Keywords: Amniotic fluid embolism; Anaphylaxis; Antibiotics; Cardiopulmonary collapse; Case report.

Publication types

  • Case Reports

MeSH terms

  • Cesarean Section / adverse effects
  • Embolism, Amniotic Fluid* / diagnosis
  • Embolism, Amniotic Fluid* / etiology
  • Female
  • Humans
  • Pregnancy
  • Shock* / complications