Abnormal Uterine Bleeding

Med Clin North Am. 2023 Mar;107(2):235-246. doi: 10.1016/j.mcna.2022.10.014. Epub 2022 Dec 26.

Abstract

Abnormal uterine bleeding is a common problem in premenopausal women and refers to uterine bleeding that is abnormal in frequency, duration, volume, and/or regularity. Etiologies can be classified using the PALM-COIEN system. Patients should receive a comprehensive history and physical with special attention to menstrual, sexual, and family history. Physical examination needs to include a pelvic examination with speculum and bimanual components. All patients need to have a pregnancy test and CBC with platelets. Treatments vary by etiology. Medical treatments include levonorgestrel intrauterine devices, oral contraceptive pills, and tranexamic acid. Surgical treatment options include endometrial ablation and hysterectomy.

Keywords: Abnormal uterine bleeding; Fibroids; Heavy menstrual bleeding; Polyps.

Publication types

  • Review

MeSH terms

  • Contraceptives, Oral
  • Female
  • Humans
  • Hysterectomy
  • Levonorgestrel
  • Menorrhagia* / diagnosis
  • Menorrhagia* / etiology
  • Menorrhagia* / therapy
  • Pregnancy
  • Uterine Hemorrhage / diagnosis
  • Uterine Hemorrhage / etiology
  • Uterine Hemorrhage / therapy

Substances

  • Levonorgestrel
  • Contraceptives, Oral