Diagnosis and Management of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Stephanie L Grach; Jaime Seltzer; Tony Y Chon; Ravindra Ganesh

doi:10.1016/j.mayocp.2023.07.032

Diagnosis and Management of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Mayo Clin Proc. 2023 Oct;98(10):1544-1551. doi: 10.1016/j.mayocp.2023.07.032.

Authors

Stephanie L Grach¹, Jaime Seltzer², Tony Y Chon³, Ravindra Ganesh³

Affiliations

¹ Division of General Internal Medicine, Department of Medicine, Mayo Clinic, Rochester, MN. Electronic address: grach.stephanie@mayo.edu.
² Myalgic Encephalomyelitis Action Network, Santa Monica, CA; Stanford School of Medicine, Stanford University, Palo Alto, CA.
³ Division of General Internal Medicine, Department of Medicine, Mayo Clinic, Rochester, MN.

PMID: 37793728
DOI: 10.1016/j.mayocp.2023.07.032

Abstract

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic neurologic disease often preceded by infection. There has been increased interest in ME/CFS recently because of its significant overlap with the post-COVID syndrome (long COVID or post-acute sequelae of COVID), with several studies estimating that half of patients with post-COVID syndrome fulfill ME/CFS criteria. Our concise review describes a generalist approach to ME/CFS, including diagnosis, evaluation, and management strategies.

Publication types

Review

MeSH terms

COVID-19 Testing
COVID-19*
Fatigue Syndrome, Chronic* / diagnosis
Fatigue Syndrome, Chronic* / etiology
Fatigue Syndrome, Chronic* / therapy
Humans
Post-Acute COVID-19 Syndrome