Glaucoma progression due to refraining examination amid the pandemic of COVID-19

Int Ophthalmol. 2024 Apr 25;44(1):196. doi: 10.1007/s10792-024-03151-4.

Abstract

Purpose: Some patients refrained from seeking an ophthalmologist due to the anxiety and morbidity associated with the coronavirus disease (COVID-19) pandemic. We investigated progressive visual field defects in patients with glaucoma who refrained from ophthalmological examinations.

Methods: This was a retrospective study. We analyzed data from 886 patients with glaucoma who visited Inouye Eye Hospital in June 2022 and were followed-up prior to January 2020. We examined the number of times patients canceled visits between January 2020 and May 2022 due to coronavirus concerns. We assessed the mean deviation (MD) values of the Humphrey Visual Field Assessment (HFA) program 30-2 SITA Standard values after visit interruptions for worsening beyond the MD values predicted by the MD slope. Factors influencing this difference were analyzed using logistic regression analysis.

Results: The study included 374 men and 512 women. The mean age was 68.7 ± 12.0 years. Visit interruptions occurred in 146 patients (16.5%), with 95 (65.1%) rescheduling once, 27 (18.5%) twice, and 24 (16.4%) three or more times. Among 90 patients who underwent HFA regularly, 50 (55.6%) experienced worse-than-expected MD values and 12 (13.3%) deteriorated by 2 dB or more. Longer interruptions and high intraocular pressure before interruption worsened the MD values by 2 dB or more.

Conclusion: Patients with glaucoma with visit interruptions due to the pandemic should be monitored for the progression of visual field impairment.

Keywords: COVID-19; Glaucoma; Interruption of visits; Visual field.

MeSH terms

  • Aged
  • Aged, 80 and over
  • COVID-19* / epidemiology
  • Disease Progression*
  • Female
  • Glaucoma* / diagnosis
  • Glaucoma* / epidemiology
  • Glaucoma* / physiopathology
  • Humans
  • Intraocular Pressure / physiology
  • Male
  • Middle Aged
  • Pandemics
  • Retrospective Studies
  • SARS-CoV-2*
  • Visual Field Tests
  • Visual Fields* / physiology