Molecular mapping of a gene cluster flanking the Drosophila Dopa decarboxylase gene

Genetics. 1984 Apr;106(4):679-94. doi: 10.1093/genetics/106.4.679.

Abstract

Nine lethal complementation groups flanking the Drosophila Dopa decarboxylase (Ddc) gene, have been localized within 100 kb of cloned chromosomal DNA. Six of these complementation groups are within 23 kb of DNA, and all ten complementation groups, including Ddc, lie within 78-82 kb of DNA. The potential significance of this unusually high gene density is discussed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aromatic-L-Amino-Acid Decarboxylases / genetics*
  • Chromosome Mapping
  • Cloning, Molecular
  • Dopa Decarboxylase / genetics*
  • Drosophila melanogaster / genetics*
  • Genes, Lethal
  • Genetic Complementation Test
  • Genetic Linkage

Substances

  • Dopa Decarboxylase
  • Aromatic-L-Amino-Acid Decarboxylases