Background: The term Marjolin ulcer is now synonymous with malignant transformation of chronic ulcers, sinus tracts, and burn scars.
Objective: To illustrate the importance of incisional or excisional biopsies in cases of suspected burn scar carcinoma.
Methods: Case report and review of the literature.
Results: Multiple punch biopsies were negative while a complete excision revealed the diagnosis of squamous cell carcinoma.
Conclusion: Because of the focal nature of malignant change in burn scars, incisional or excisional biopsy should be performed.