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PXD019645

PXD019645 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleData, reagents, assays and merits of proteomics for SARS-CoV-2 research and testing
DescriptionAs the SARS-CoV-2 pandemic continues to spread, thousands of scientists around the globe have changed research direction to understand better how the virus works and to find out how it may be tackled. To facilitate proteomic research on SARS-CoV-2, we presents deep-scale proteomes of common cell line models (Calu-3, Caco-2, ACE2 transfected A549 and Vero E6) and monitors changes of the proteome upon viral infection in Vero E6 cells. We provide high quality proteome expression data that can be used to refine the annotation of protein coding regions of the Vero E6 cell line genome. Further, we generated spectral libraries that can be used DIA cell line experiments or PRM assays of SARS-CoV-2 proteins.
HostingRepositoryPRIDE
AnnounceDate2023-05-15
AnnouncementXMLSubmission_2023-05-15_02:20:49.180.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterChien-YunLee
SpeciesList scientific name: Cercopithecus aethiops (Green monkey) (Grivet); NCBI TaxID: 9534; scientific name: Homo sapiens (Human); NCBI TaxID: 9606; scientific name: Chlorocebus sabaeus; NCBI TaxID: 60711;
ModificationListmono N-acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-06-08 04:54:13ID requested
12020-06-28 23:18:01announced
22020-06-30 04:05:46announced2020-06-30: Updated publication reference for PubMed record(s): 32591346.
2020-06-30: Updated publication reference for DOI(s): 10.1074/mcp.RA120.002164.
32023-05-15 02:20:50announced2023-05-15: Updated project metadata.
Publication List
Zecha J, Lee CY, Bayer FP, Meng C, Grass V, Zerweck J, Schnatbaum K, Michler T, Pichlmair A, Ludwig C, Kuster B, Data, Reagents, Assays and Merits of Proteomics for SARS-CoV-2 Research and Testing. Mol Cell Proteomics, 19(9):1503-1522(2020) [pubmed]
Keyword List
ProteomeXchange project tag: Sars-cov-2, Covid-19, EPIC-XS
submitter keyword: SARS-CoV-2, Vero E6, stable isotope labeling, clinical proteomics, parallel reaction monitoring, infectome, COVID-19, ACE2
Contact List
BernhardKuster
contact affiliationChair of Proteomics and Bioanalytics, Technical University of Munich, Germany
contact emailkuster@tum.de
lab head
Chien-YunLee
contact affiliationChair of Proteomics and Bioanalytics, Technical University of Munich, Germany
contact emailchienyun.lee@tum.de
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
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