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What is Reactome ?
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Cannabinoids [extracellular region]
Stable Identifier
R-ALL-444560
Type
Set [DefinedSet]
Compartment
extracellular region
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Danio rerio
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Signal Transduction (Bos taurus)
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (i) signalling events (Bos taurus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
CNRs:Cannabinoids [plasma membrane] (Bos taurus)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
CNRs:Cannabinoids [plasma membrane] (Bos taurus)
Cannabinoids [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
CNRs:Cannabinoids [plasma membrane] (Bos taurus)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
CNRs:Cannabinoids [plasma membrane] (Bos taurus)
Cannabinoids [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
CNRs:Cannabinoids [plasma membrane] (Bos taurus)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
CNRs:Cannabinoids [plasma membrane] (Bos taurus)
Cannabinoids [extracellular region]
GPCR ligand binding (Bos taurus)
Class A/1 (Rhodopsin-like receptors) (Bos taurus)
Cannabinoid receptors can bind cannabinoids (Bos taurus)
Cannabinoids [extracellular region]
CNRs:Cannabinoids [plasma membrane] (Bos taurus)
Cannabinoids [extracellular region]
Signal Transduction (Canis familiaris)
Signaling by GPCR (Canis familiaris)
GPCR downstream signalling (Canis familiaris)
G alpha (i) signalling events (Canis familiaris)
Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
CNRs:Cannabinoids [plasma membrane] (Canis familiaris)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
CNRs:Cannabinoids [plasma membrane] (Canis familiaris)
Cannabinoids [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
CNRs:Cannabinoids [plasma membrane] (Canis familiaris)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
CNRs:Cannabinoids [plasma membrane] (Canis familiaris)
Cannabinoids [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
CNRs:Cannabinoids [plasma membrane] (Canis familiaris)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
CNRs:Cannabinoids [plasma membrane] (Canis familiaris)
Cannabinoids [extracellular region]
GPCR ligand binding (Canis familiaris)
Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
Cannabinoid receptors can bind cannabinoids (Canis familiaris)
Cannabinoids [extracellular region]
CNRs:Cannabinoids [plasma membrane] (Canis familiaris)
Cannabinoids [extracellular region]
Signal Transduction (Danio rerio)
Signaling by GPCR (Danio rerio)
GPCR downstream signalling (Danio rerio)
G alpha (i) signalling events (Danio rerio)
Liganded Gi-activating GPCR acts as a GEF for Gi (Danio rerio)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
CNRs:Cannabinoids [plasma membrane] (Danio rerio)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
CNRs:Cannabinoids [plasma membrane] (Danio rerio)
Cannabinoids [extracellular region]
GPCR ligand binding (Danio rerio)
Class A/1 (Rhodopsin-like receptors) (Danio rerio)
Cannabinoid receptors can bind cannabinoids (Danio rerio)
Cannabinoids [extracellular region]
CNRs:Cannabinoids [plasma membrane] (Danio rerio)
Cannabinoids [extracellular region]
Signal Transduction (Gallus gallus)
Signaling by GPCR (Gallus gallus)
GPCR downstream signalling (Gallus gallus)
G alpha (i) signalling events (Gallus gallus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Gallus gallus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
CNRs:Cannabinoids [plasma membrane] (Gallus gallus)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
CNRs:Cannabinoids [plasma membrane] (Gallus gallus)
Cannabinoids [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
CNRs:Cannabinoids [plasma membrane] (Gallus gallus)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
CNRs:Cannabinoids [plasma membrane] (Gallus gallus)
Cannabinoids [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
CNRs:Cannabinoids [plasma membrane] (Gallus gallus)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
CNRs:Cannabinoids [plasma membrane] (Gallus gallus)
Cannabinoids [extracellular region]
GPCR ligand binding (Gallus gallus)
Class A/1 (Rhodopsin-like receptors) (Gallus gallus)
Cannabinoid receptors can bind cannabinoids (Gallus gallus)
Cannabinoids [extracellular region]
CNRs:Cannabinoids [plasma membrane] (Gallus gallus)
Cannabinoids [extracellular region]
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CNRs:Cannabinoids [plasma membrane] (Homo sapiens)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CNRs:Cannabinoids [plasma membrane] (Homo sapiens)
Cannabinoids [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CNRs:Cannabinoids [plasma membrane] (Homo sapiens)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CNRs:Cannabinoids [plasma membrane] (Homo sapiens)
Cannabinoids [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CNRs:Cannabinoids [plasma membrane] (Homo sapiens)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CNRs:Cannabinoids [plasma membrane] (Homo sapiens)
Cannabinoids [extracellular region]
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Cannabinoid receptors can bind cannabinoids (Homo sapiens)
Cannabinoids [extracellular region]
CNRs:Cannabinoids [plasma membrane] (Homo sapiens)
Cannabinoids [extracellular region]
Signal Transduction (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (i) signalling events (Mus musculus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
CNRs:Cannabinoids [plasma membrane] (Mus musculus)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
CNRs:Cannabinoids [plasma membrane] (Mus musculus)
Cannabinoids [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
CNRs:Cannabinoids [plasma membrane] (Mus musculus)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
CNRs:Cannabinoids [plasma membrane] (Mus musculus)
Cannabinoids [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
CNRs:Cannabinoids [plasma membrane] (Mus musculus)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
CNRs:Cannabinoids [plasma membrane] (Mus musculus)
Cannabinoids [extracellular region]
GPCR ligand binding (Mus musculus)
Class A/1 (Rhodopsin-like receptors) (Mus musculus)
Cannabinoid receptors can bind cannabinoids (Mus musculus)
Cannabinoids [extracellular region]
CNRs:Cannabinoids [plasma membrane] (Mus musculus)
Cannabinoids [extracellular region]
Signal Transduction (Rattus norvegicus)
Signaling by GPCR (Rattus norvegicus)
GPCR downstream signalling (Rattus norvegicus)
G alpha (i) signalling events (Rattus norvegicus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Rattus norvegicus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
CNRs:Cannabinoids [plasma membrane] (Rattus norvegicus)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Rattus norvegicus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
CNRs:Cannabinoids [plasma membrane] (Rattus norvegicus)
Cannabinoids [extracellular region]
GPCR ligand binding (Rattus norvegicus)
Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
Cannabinoid receptors can bind cannabinoids (Rattus norvegicus)
Cannabinoids [extracellular region]
CNRs:Cannabinoids [plasma membrane] (Rattus norvegicus)
Cannabinoids [extracellular region]
Signal Transduction (Sus scrofa)
Signaling by GPCR (Sus scrofa)
GPCR downstream signalling (Sus scrofa)
G alpha (i) signalling events (Sus scrofa)
Liganded Gi-activating GPCR acts as a GEF for Gi (Sus scrofa)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
CNRs:Cannabinoids [plasma membrane] (Sus scrofa)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
CNRs:Cannabinoids [plasma membrane] (Sus scrofa)
Cannabinoids [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
CNRs:Cannabinoids [plasma membrane] (Sus scrofa)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
CNRs:Cannabinoids [plasma membrane] (Sus scrofa)
Cannabinoids [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
CNRs:Cannabinoids [plasma membrane] (Sus scrofa)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
CNRs:Cannabinoids [plasma membrane] (Sus scrofa)
Cannabinoids [extracellular region]
GPCR ligand binding (Sus scrofa)
Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
Cannabinoid receptors can bind cannabinoids (Sus scrofa)
Cannabinoids [extracellular region]
CNRs:Cannabinoids [plasma membrane] (Sus scrofa)
Cannabinoids [extracellular region]
Signal Transduction (Xenopus tropicalis)
Signaling by GPCR (Xenopus tropicalis)
GPCR downstream signalling (Xenopus tropicalis)
G alpha (i) signalling events (Xenopus tropicalis)
Liganded Gi-activating GPCR acts as a GEF for Gi (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
CNRs:Cannabinoids [plasma membrane] (Xenopus tropicalis)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
CNRs:Cannabinoids [plasma membrane] (Xenopus tropicalis)
Cannabinoids [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
CNRs:Cannabinoids [plasma membrane] (Xenopus tropicalis)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
CNRs:Cannabinoids [plasma membrane] (Xenopus tropicalis)
Cannabinoids [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
CNRs:Cannabinoids [plasma membrane] (Xenopus tropicalis)
Cannabinoids [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
CNRs:Cannabinoids [plasma membrane] (Xenopus tropicalis)
Cannabinoids [extracellular region]
GPCR ligand binding (Xenopus tropicalis)
Class A/1 (Rhodopsin-like receptors) (Xenopus tropicalis)
Cannabinoid receptors can bind cannabinoids (Xenopus tropicalis)
Cannabinoids [extracellular region]
CNRs:Cannabinoids [plasma membrane] (Xenopus tropicalis)
Cannabinoids [extracellular region]
Participants
members
AEA [extracellular region]
2AG [extracellular region]
Participates
as an input of
Cannabinoid receptors can bind cannabinoids (Gallus gallus)
Cannabinoid receptors can bind cannabinoids (Xenopus tropicalis)
Cannabinoid receptors can bind cannabinoids (Danio rerio)
Cannabinoid receptors can bind cannabinoids (Sus scrofa)
Cannabinoid receptors can bind cannabinoids (Bos taurus)
Cannabinoid receptors can bind cannabinoids (Canis familiaris)
Cannabinoid receptors can bind cannabinoids (Rattus norvegicus)
Cannabinoid receptors can bind cannabinoids (Mus musculus)
Cannabinoid receptors can bind cannabinoids (Homo sapiens)
as a component of
CNRs:Cannabinoids [plasma membrane] (Xenopus tropicalis)
CNRs:Cannabinoids [plasma membrane] (Bos taurus)
CNRs:Cannabinoids [plasma membrane] (Rattus norvegicus)
CNRs:Cannabinoids [plasma membrane] (Mus musculus)
CNRs:Cannabinoids [plasma membrane] (Sus scrofa)
CNRs:Cannabinoids [plasma membrane] (Danio rerio)
CNRs:Cannabinoids [plasma membrane] (Canis familiaris)
CNRs:Cannabinoids [plasma membrane] (Gallus gallus)
CNRs:Cannabinoids [plasma membrane] (Homo sapiens)
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