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Activation of TRKA receptors
Stable Identifier
R-HSA-187015
DOI
10.3180/REACT_11064.3
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
Locations in the PathwayBrowser
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Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by NTRKs (Homo sapiens)
Signaling by NTRK1 (TRKA) (Homo sapiens)
Activation of TRKA receptors (Homo sapiens)
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Trk receptors can either be activated by neurotrophins or by two G-protein-coupled receptors (GPCRs) although the biological relevance of GPCRs remains to be shown.
Literature References
PubMed ID
Title
Journal
Year
16939974
Neurotrophin-regulated signalling pathways
Reichardt, LF
Philos Trans R Soc Lond B Biol Sci
2006
Participants
Events
TRKA activation by NGF
(Homo sapiens)
NGF-independant TRKA activation
(Homo sapiens)
Participates
as an event of
Signaling by NTRK1 (TRKA) (Homo sapiens)
Event Information
Go Biological Process
transmembrane receptor protein tyrosine kinase signaling pathway (0007169)
Orthologous Events
Activation of TRKA receptors (Bos taurus)
Activation of TRKA receptors (Canis familiaris)
Activation of TRKA receptors (Gallus gallus)
Activation of TRKA receptors (Mus musculus)
Activation of TRKA receptors (Rattus norvegicus)
Activation of TRKA receptors (Sus scrofa)
Activation of TRKA receptors (Xenopus tropicalis)
Authored
Nasi, S (2006-10-10)
Annibali, D (2006-10-10)
Reviewed
Greene, LA (2007-11-08)
Created
Jassal, B (2006-09-07)
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