Metabolism of RNA

Stable Identifier
R-HSA-8953854
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
Locations in the PathwayBrowser
General
Click the image above or here to open this pathway in the Pathway Browser
This superpathway encompasses the processes by which RNA transcription products are further modified covalently and non-covalently to yield their mature forms, and the regulation of these processes. Annotated pathways include ones for capping, splicing, and 3'-cleavage and polyadenylation to yield mature mRNA molecules that are exported from the nucleus (Hocine et al. 2010). mRNA editing and nonsense-mediated decay are also annotated. Processes leading to mRNA breakdown are described: deadenylation-dependent mRNA decay, microRNA-mediated RNA cleavage, and regulation of mRNA stability by proteins that bind AU-rich elements.psnRNP assembly is also annotated here.

The aminoacylation of mature tRNAs is annotated in the "Metabolism of proteins" superpathway, as a part of "Translation".

Literature References
PubMed ID Title Journal Year
20961978 RNA processing and export

Singer, RH, Grünwald, D, Hocine, S

Cold Spring Harb Perspect Biol 2010
Participants
Event Information
Go Biological Process
Orthologous Events
Authored
Reviewed
Created
Cite Us!