The model reproduces the time profiles of p27, E2F and aE/cdk2 as depicted in Figure 5 c of the paper. Model was simulated on MathSBML.
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To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
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The kinetic origins of the restriction point in the mammalian cell cycle.
- B D Aguda, Y Tang
- Cell proliferation , 10/ 1999 , Volume 32 , Issue 5 , pages: 321-335 , PubMed ID: 10619492
Submitter of this revision: Lucian Smith
Curator: Lucian Smith
Modeller: Nicolas Le Novère
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