|
| Status |
Public on Jan 31, 2010 |
| Title |
mRNA and miRNA expression in parietal lobe cortex in Alzheimer's disease |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
Non-coding RNA profiling by array
|
| Summary |
In this study, we jointly profiled mRNA and miRNA expression to determine the role of miRNAs in AD, and whether the levels of miRNAs are related to those of target mRNAs. We found a bias towards positive correlation between levels of miRNAs and those of their targets.
|
| |
|
| Overall design |
We profiled parietal lobe tissue from 4 AD patients and 4 age-matched controls.
|
| |
|
| Contributor(s) |
Zhou XJ, Finch CE, Nunez-Iglesias J, Liu C, Morgan TE |
| Citation(s) |
20126538 |
| Submission date |
Jun 23, 2009 |
| Last update date |
Jun 26, 2019 |
| Contact name |
Juan Nunez-Iglesias |
| E-mail(s) |
nunezigl@usc.edu
|
| Organization name |
University of Southern California
|
| Department |
Computational Biology
|
| Lab |
Xianghong Jasmine Zhou
|
| Street address |
1050 Childs Way, RRI-201
|
| City |
Los Angeles |
| State/province |
CA |
| ZIP/Postal code |
90089-2910 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
| GPL8757 |
USC/XJZ Human 0.9 K miRNA-940-v1.0 |
|
| Samples (16)
|
| GSM420145 |
mRNA parietal lobe Alzheimer's disease number 3 |
| GSM420146 |
mRNA parietal lobe Alzheimer's disease number 12 |
| GSM420147 |
mRNA parietal lobe Alzheimer's disease number 2 |
| GSM420148 |
mRNA parietal lobe Alzheimer's disease number 16 |
| GSM420149 |
mRNA parietal lobe Control number 15 |
| GSM420150 |
mRNA parietal lobe Control number 6 |
| GSM420151 |
mRNA parietal lobe Control number 18 |
| GSM420152 |
mRNA parietal lobe Control number 10 |
| GSM420156 |
miRNA parietal lobe Alzheimer's disease number 3 |
| GSM420157 |
miRNA parietal lobe Alzheimer's disease number 12 |
| GSM420158 |
miRNA parietal lobe Alzheimer's disease number 2 |
| GSM420159 |
miRNA parietal lobe Alzheimer's disease number 16 |
| GSM420160 |
miRNA parietal lobe Control number 15 |
| GSM420161 |
miRNA parietal lobe Control number 6 |
| GSM420162 |
miRNA parietal lobe Control number 18 |
| GSM420163 |
miRNA parietal lobe Control number 10 |
|
| Relations |
| BioProject |
PRJNA117471 |
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