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Series GSE108576 Query DataSets for GSE108576
Status Public on Aug 28, 2018
Title Epigenetic profiling for the molecular classification of metastatic brain tumors
Organism Homo sapiens
Experiment type Methylation profiling by array
Summary Genome-wide DNA methylation profiling of brain metastases from lung cancer, breast cancer, and melanoma samples. The Illumina Infinium 450K Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 450,000 methylation sites in formalin-fixed paraffin-embedded (FFPE) samples from brain metastases. Samples included 30 breast cancer brain metastases, 18 lung cancer brain metastases, 37 melanoma brain metastases, and 4 samples with brain metastases from patients with uncertain primary.
 
Overall design Bisulfite converted DNA samples from 89 specimens were analyzed by using the Illumina Infinium 450K Human Methylation BeadChip.
 
Contributor(s) Salomon MP, Marzese DM, Hoon DS, Orozco JI
Citation(s) 30401823
Submission date Dec 27, 2017
Last update date Apr 15, 2022
Contact name Dave S.B. Hoon
E-mail(s) hoond@jwci.org
Organization name Saint John's Cancer Institute
Department Translational Molecular Medicine
Street address 2200 Santa Monica Boulevard
City Santa Monica
State/province CA
ZIP/Postal code 90403
Country USA
 
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (89)
GSM2905348 Genomic DNA from Breast cancer brain metastasis-01
GSM2905349 Genomic DNA from Breast cancer brain metastasis-02
GSM2905350 Genomic DNA from Breast cancer brain metastasis-03
Relations
BioProject PRJNA427718

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE108576_RAW.tar 903.6 Mb (http)(custom) TAR (of IDAT)
GSE108576_hoond_12-22-17_betas.txt.gz 217.4 Mb (ftp)(http) TXT
GSE108576_hoond_12-22-17_signal.txt.gz 242.6 Mb (ftp)(http) TXT
Processed data are available on Series record
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