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| Status |
Public on Apr 29, 2019 |
| Title |
Human brain tissues from healthy controls and multiple sclerosis patients |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Multiple sclerosis (MS) is characterized by cell proliferation, migration and damage in various cell types in different CNS regions and causes disabilities related to distinct neurological pathways, such as walking, vision and cognition. Here, region-specific transcriptomic approach was used to determine changes in gene expression in five different CNS regions (hippocampus, frontal cortex, internal capsule, corpus callosum, and parietal cortex) in MS.
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| Overall design |
Five MS patients (average age = 57.6 years) and five age-matched healthy controls (average age = 56.2 years) fresh frozen autopsy samples were obtained from Human Brain and Spinal Fluid Research Center in Los Angeles.
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| |
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| Contributor(s) |
Itoh Y, Voskuhl RR |
| Citation(s) |
31040210 |
| Submission date |
Dec 07, 2018 |
| Last update date |
Jul 29, 2019 |
| Contact name |
Yuichiro Itoh |
| E-mail(s) |
yitoh@ucla.edu
|
| Phone |
3102068999
|
| Organization name |
UCLA
|
| Department |
Neurology
|
| Street address |
635 Charles E. Young Drive South
|
| City |
Los Angeles |
| State/province |
California |
| ZIP/Postal code |
90095 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL21290 |
Illumina HiSeq 3000 (Homo sapiens) |
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| Samples (50)
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| Relations |
| BioProject |
PRJNA508944 |
| SRA |
SRP173190 |
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