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Showing metabocard for (+)-Limonene (HMDB0003375)

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Record Information
Version5.0
StatusDetected and Quantified
Creation Date2006-08-12 19:51:01 UTC
Update Date2022-03-07 02:49:18 UTC
HMDB IDHMDB0003375
Secondary Accession Numbers
  • HMDB03375
Metabolite Identification
Common Name(+)-Limonene
Description
Structure
Thumb
MOL3D MOLSDF3D SDFPDB3D PDBSMILESInChI

MOL for HMDB0003375 ((+)-Limonene)

  Mrv1652309272007452D          

 10 10  0  0  0  0            999 V2000
    0.5360    1.1152    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5360    1.9402    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2505    0.7027    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3218   -0.5347    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8928    1.1152    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6073    0.7027    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6073   -0.1223    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8928   -0.5347    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1783   -0.1223    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1783    0.7027    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  1  3  1  0  0  0  0
  5  6  1  0  0  0  0
  5 10  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
  7  4  1  0  0  0  0
 10  1  1  1  0  0  0
M  END
Download

3D MOL for HMDB0003375 ((+)-Limonene)

HMDB0003375
     RDKit          3D
(+)-Limonene
 26 26  0  0  0  0  0  0  0  0999 V2000
   -2.7208    0.9557   -0.3367 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0563   -0.0832    0.0951 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7607   -1.4175    0.1794 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6442   -0.1004    0.5258 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.0438   -1.1544   -0.3387 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5044   -1.0564   -0.1664 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0583    0.1470   -0.3519 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4957    0.3724   -0.2103 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0690    1.2304   -0.7133 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0697    1.1984    0.4553 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3234    1.9549   -0.4391 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7652    0.8585   -0.6302 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6725   -1.8362    1.2042 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3341   -2.1063   -0.5698 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8352   -1.2972   -0.0889 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6266   -0.5178    1.5743 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3535   -2.1568   -0.0838 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2364   -0.9019   -1.3924 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1481   -1.9035    0.1012 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.7633    1.2996   -0.7626 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.0288   -0.4672   -0.7021 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.8312    0.4134    0.8435 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5329    2.2146   -0.7456 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5742    0.9991   -1.6655 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5330    2.1017    0.4992 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.7424    1.2533    1.3646 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  3
  2  3  1  0
  2  4  1  0
  4  5  1  0
  5  6  1  0
  6  7  2  0
  7  8  1  0
  7  9  1  0
  9 10  1  0
 10  4  1  0
  1 11  1  0
  1 12  1  0
  3 13  1  0
  3 14  1  0
  3 15  1  0
  4 16  1  1
  5 17  1  0
  5 18  1  0
  6 19  1  0
  8 20  1  0
  8 21  1  0
  8 22  1  0
  9 23  1  0
  9 24  1  0
 10 25  1  0
 10 26  1  0
M  END
Download

3D SDF for HMDB0003375 ((+)-Limonene)

  Mrv1652309272007452D          

 10 10  0  0  0  0            999 V2000
    0.5360    1.1152    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5360    1.9402    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2505    0.7027    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3218   -0.5347    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8928    1.1152    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6073    0.7027    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6073   -0.1223    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8928   -0.5347    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1783   -0.1223    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1783    0.7027    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  1  3  1  0  0  0  0
  5  6  1  0  0  0  0
  5 10  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
  7  4  1  0  0  0  0
 10  1  1  1  0  0  0
M  END
> <DATABASE_ID>
HMDB0003375

> <DATABASE_NAME>
hmdb

> <SMILES>
CC(=C)[C@@H]1CCC(C)=CC1

> <INCHI_IDENTIFIER>
InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1

> <INCHI_KEY>
XMGQYMWWDOXHJM-JTQLQIEISA-N

> <FORMULA>
C10H16

> <MOLECULAR_WEIGHT>
136.234

> <EXACT_MASS>
136.125200512

> <JCHEM_ACCEPTOR_COUNT>
0

> <JCHEM_ATOM_COUNT>
26

> <JCHEM_AVERAGE_POLARIZABILITY>
17.54931315245657

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene

> <ALOGPS_LOGP>
4.50

> <JCHEM_LOGP>
3.2198126516666665

> <ALOGPS_LOGS>
-2.47

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
1

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_POLAR_SURFACE_AREA>
0.0

> <JCHEM_REFRACTIVITY>
46.4803

> <JCHEM_ROTATABLE_BOND_COUNT>
1

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
4.57e-01 g/l

> <JCHEM_TRADITIONAL_IUPAC>
α-limonene

> <JCHEM_VEBER_RULE>
1

$$$$
Download

3D-SDF for HMDB0003375 ((+)-Limonene)

HMDB0003375
     RDKit          3D
(+)-Limonene
 26 26  0  0  0  0  0  0  0  0999 V2000
   -2.7208    0.9557   -0.3367 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0563   -0.0832    0.0951 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7607   -1.4175    0.1794 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6442   -0.1004    0.5258 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.0438   -1.1544   -0.3387 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5044   -1.0564   -0.1664 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0583    0.1470   -0.3519 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4957    0.3724   -0.2103 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0690    1.2304   -0.7133 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0697    1.1984    0.4553 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3234    1.9549   -0.4391 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7652    0.8585   -0.6302 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6725   -1.8362    1.2042 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3341   -2.1063   -0.5698 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8352   -1.2972   -0.0889 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6266   -0.5178    1.5743 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3535   -2.1568   -0.0838 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2364   -0.9019   -1.3924 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1481   -1.9035    0.1012 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.7633    1.2996   -0.7626 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.0288   -0.4672   -0.7021 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.8312    0.4134    0.8435 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.5329    2.2146   -0.7456 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5742    0.9991   -1.6655 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5330    2.1017    0.4992 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.7424    1.2533    1.3646 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  3
  2  3  1  0
  2  4  1  0
  4  5  1  0
  5  6  1  0
  6  7  2  0
  7  8  1  0
  7  9  1  0
  9 10  1  0
 10  4  1  0
  1 11  1  0
  1 12  1  0
  3 13  1  0
  3 14  1  0
  3 15  1  0
  4 16  1  1
  5 17  1  0
  5 18  1  0
  6 19  1  0
  8 20  1  0
  8 21  1  0
  8 22  1  0
  9 23  1  0
  9 24  1  0
 10 25  1  0
 10 26  1  0
M  END
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PDB for HMDB0003375 ((+)-Limonene)

HEADER    PROTEIN                                 27-SEP-20   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   27-SEP-20         0                                  
HETATM    1  C   UNK     0       1.001   2.082   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0       1.001   3.622   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       2.334   1.312   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -4.334  -0.998   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      -1.667   2.082   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      -3.000   1.312   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      -3.000  -0.228   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      -1.667  -0.998   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0      -0.333  -0.228   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      -0.333   1.312   0.000  0.00  0.00           C+0
CONECT    1    2    3   10                                                  
CONECT    2    1                                                            
CONECT    3    1                                                            
CONECT    4    7                                                            
CONECT    5    6   10                                                       
CONECT    6    5    7                                                       
CONECT    7    6    8    4                                                  
CONECT    8    7    9                                                       
CONECT    9    8   10                                                       
CONECT   10    5    9    1                                                  
MASTER        0    0    0    0    0    0    0    0   10    0   20    0
END
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3D PDB for HMDB0003375 ((+)-Limonene)

COMPND    HMDB0003375
HETATM    1  C1  UNL     1      -2.721   0.956  -0.337  1.00  0.00           C  
HETATM    2  C2  UNL     1      -2.056  -0.083   0.095  1.00  0.00           C  
HETATM    3  C3  UNL     1      -2.761  -1.418   0.179  1.00  0.00           C  
HETATM    4  C4  UNL     1      -0.644  -0.100   0.526  1.00  0.00           C  
HETATM    5  C5  UNL     1       0.044  -1.154  -0.339  1.00  0.00           C  
HETATM    6  C6  UNL     1       1.504  -1.056  -0.166  1.00  0.00           C  
HETATM    7  C7  UNL     1       2.058   0.147  -0.352  1.00  0.00           C  
HETATM    8  C8  UNL     1       3.496   0.372  -0.210  1.00  0.00           C  
HETATM    9  C9  UNL     1       1.069   1.230  -0.713  1.00  0.00           C  
HETATM   10  C10 UNL     1       0.070   1.198   0.455  1.00  0.00           C  
HETATM   11  H1  UNL     1      -2.323   1.955  -0.439  1.00  0.00           H  
HETATM   12  H2  UNL     1      -3.765   0.858  -0.630  1.00  0.00           H  
HETATM   13  H3  UNL     1      -2.673  -1.836   1.204  1.00  0.00           H  
HETATM   14  H4  UNL     1      -2.334  -2.106  -0.570  1.00  0.00           H  
HETATM   15  H5  UNL     1      -3.835  -1.297  -0.089  1.00  0.00           H  
HETATM   16  H6  UNL     1      -0.627  -0.518   1.574  1.00  0.00           H  
HETATM   17  H7  UNL     1      -0.353  -2.157  -0.084  1.00  0.00           H  
HETATM   18  H8  UNL     1      -0.236  -0.902  -1.392  1.00  0.00           H  
HETATM   19  H9  UNL     1       2.148  -1.903   0.101  1.00  0.00           H  
HETATM   20  H10 UNL     1       3.763   1.300  -0.763  1.00  0.00           H  
HETATM   21  H11 UNL     1       4.029  -0.467  -0.702  1.00  0.00           H  
HETATM   22  H12 UNL     1       3.831   0.413   0.843  1.00  0.00           H  
HETATM   23  H13 UNL     1       1.533   2.215  -0.746  1.00  0.00           H  
HETATM   24  H14 UNL     1       0.574   0.999  -1.666  1.00  0.00           H  
HETATM   25  H15 UNL     1      -0.533   2.102   0.499  1.00  0.00           H  
HETATM   26  H16 UNL     1       0.742   1.253   1.365  1.00  0.00           H  
CONECT    1    2    2   11   12
CONECT    2    3    4
CONECT    3   13   14   15
CONECT    4    5   10   16
CONECT    5    6   17   18
CONECT    6    7    7   19
CONECT    7    8    9
CONECT    8   20   21   22
CONECT    9   10   23   24
CONECT   10   25   26
END
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SMILES for HMDB0003375 ((+)-Limonene)

CC(=C)[C@@H]1CCC(C)=CC1
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INCHI for HMDB0003375 ((+)-Limonene)

InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1
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View in JSmolView Stereo Labels
Synonyms
Chemical FormulaC10H16
Average Molecular Weight136.234
Monoisotopic Molecular Weight136.125200512
IUPAC Name(4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene
Traditional Nameα-limonene
CAS Registry Number5989-27-5
SMILES
CC(=C)[C@@H]1CCC(C)=CC1
InChI Identifier
InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1
InChI KeyXMGQYMWWDOXHJM-JTQLQIEISA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as menthane monoterpenoids. These are monoterpenoids with a structure based on the o-, m-, or p-menthane backbone. P-menthane consists of the cyclohexane ring with a methyl group and a (2-methyl)-propyl group at the 1 and 4 ring position, respectively. The o- and m- menthanes are much rarer, and presumably arise by alkyl migration of p-menthanes.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassPrenol lipids
Sub ClassMonoterpenoids
Direct ParentMenthane monoterpenoids
Alternative Parents
Substituents
  • P-menthane monoterpenoid
  • Monocyclic monoterpenoid
  • Branched unsaturated hydrocarbon
  • Cycloalkene
  • Cyclic olefin
  • Unsaturated aliphatic hydrocarbon
  • Unsaturated hydrocarbon
  • Olefin
  • Hydrocarbon
  • Aliphatic homomonocyclic compound
Molecular FrameworkAliphatic homomonocyclic compounds
External Descriptors
Ontology
Physiological effect
Organoleptic effect
Disposition
Biological locationRoute of exposureSource
Process
Naturally occurring process
Role
Biological roleIndustrial application
Physical Properties
StateLiquid
Experimental Molecular Properties
PropertyValueReference
Melting Point-90 °CNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogP4.38GRIFFIN,S ET AL. (1999)
Experimental Chromatographic PropertiesNot Available
Predicted Molecular Properties
Predicted Chromatographic Properties
Spectra
Biological Properties
Cellular Locations
  • Cytoplasm
  • Extracellular
  • Membrane (predicted from logP)
Biospecimen Locations
  • Blood
  • Breath
  • Feces
  • Saliva
  • Urine
Tissue Locations
  • Epidermis
Pathways
Normal Concentrations
Abnormal Concentrations
Associated Disorders and Diseases
Disease References
Asthma
  1. Gahleitner F, Guallar-Hoyas C, Beardsmore CS, Pandya HC, Thomas CP: Metabolomics pilot study to identify volatile organic compound markers of childhood asthma in exhaled breath. Bioanalysis. 2013 Sep;5(18):2239-47. doi: 10.4155/bio.13.184. [PubMed:24053239 ]
Ulcerative colitis
  1. Garner CE, Smith S, de Lacy Costello B, White P, Spencer R, Probert CS, Ratcliffe NM: Volatile organic compounds from feces and their potential for diagnosis of gastrointestinal disease. FASEB J. 2007 Jun;21(8):1675-88. Epub 2007 Feb 21. [PubMed:17314143 ]
Nonalcoholic fatty liver disease
  1. Raman M, Ahmed I, Gillevet PM, Probert CS, Ratcliffe NM, Smith S, Greenwood R, Sikaroodi M, Lam V, Crotty P, Bailey J, Myers RP, Rioux KP: Fecal microbiome and volatile organic compound metabolome in obese humans with nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol. 2013 Jul;11(7):868-75.e1-3. doi: 10.1016/j.cgh.2013.02.015. Epub 2013 Feb 27. [PubMed:23454028 ]
Autism
  1. De Angelis M, Piccolo M, Vannini L, Siragusa S, De Giacomo A, Serrazzanetti DI, Cristofori F, Guerzoni ME, Gobbetti M, Francavilla R: Fecal microbiota and metabolome of children with autism and pervasive developmental disorder not otherwise specified. PLoS One. 2013 Oct 9;8(10):e76993. doi: 10.1371/journal.pone.0076993. eCollection 2013. [PubMed:24130822 ]
Pervasive developmental disorder not otherwise specified
  1. De Angelis M, Piccolo M, Vannini L, Siragusa S, De Giacomo A, Serrazzanetti DI, Cristofori F, Guerzoni ME, Gobbetti M, Francavilla R: Fecal microbiota and metabolome of children with autism and pervasive developmental disorder not otherwise specified. PLoS One. 2013 Oct 9;8(10):e76993. doi: 10.1371/journal.pone.0076993. eCollection 2013. [PubMed:24130822 ]
Perillyl alcohol administration for cancer treatment
  1. Silva CL, Passos M, Camara JS: Solid phase microextraction, mass spectrometry and metabolomic approaches for detection of potential urinary cancer biomarkers--a powerful strategy for breast cancer diagnosis. Talanta. 2012 Jan 30;89:360-8. doi: 10.1016/j.talanta.2011.12.041. Epub 2011 Dec 22. [PubMed:22284503 ]
Associated OMIM IDs
DrugBank IDDB08921
Phenol Explorer Compound IDNot Available
FooDB IDFDB006329
KNApSAcK IDC00010868
Chemspider ID389747
KEGG Compound IDC06099
BioCyc IDCPD-4886
BiGG IDNot Available
Wikipedia LinkLimonene
METLIN IDNot Available
PubChem Compound440917
PDB IDNot Available
ChEBI ID15382
Food Biomarker OntologyNot Available
VMH IDLIMNEN
MarkerDB IDNot Available
Good Scents IDNot Available
References
Synthesis Referencev. Braun, Julius; Lemke, Georg. Preparation of pure d- and l-limonene. Berichte der Deutschen Chemischen Gesellschaft [Abteilung] B: Abhandlungen (1923), 56B 1562-3.
Material Safety Data Sheet (MSDS)Not Available
General References

Enzymes

Enzyme Details
1. Cytochrome P450 2C9
General function:
Involved in monooxygenase activity
Specific function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. This enzyme contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S-warfarin, diclofenac, phenytoin, tolbutamide and losartan.
Gene Name:
CYP2C9
Uniprot ID:
P11712
Molecular weight:
55627.365
Reactions
(+)-Limonene + NADPH + Oxygen → (+)-trans-Carveol + NADP + Waterdetails
(+)-Limonene + NADPH + Oxygen → (-)-trans-Carveol + NADP + Waterdetails
(+)-Limonene + NADPH + Oxygen → (S)-p-Mentha-1,8-dien-7-ol + NADP + Waterdetails
Enzyme Details
2. Cytochrome P450 2C19
General function:
Involved in monooxygenase activity
Specific function:
Responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine.
Gene Name:
CYP2C19
Uniprot ID:
P33261
Molecular weight:
55944.565
Reactions
(+)-Limonene + NADPH + Oxygen → (+)-trans-Carveol + NADP + Waterdetails
(+)-Limonene + NADPH + Oxygen → (-)-trans-Carveol + NADP + Waterdetails
(+)-Limonene + NADPH + Oxygen → (S)-p-Mentha-1,8-dien-7-ol + NADP + Waterdetails