U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

De Quervain disease

MedGen UID:
101771
•Concept ID:
C0149870
•
Disease or Syndrome
Synonyms: De Quervain Disease; De Quervain Stenosing Tenosynovitis; De Quervain's Disease; De Quervains Disease; Disease, De Quervain; Stenosing Tenosynovitis, De Quervain
SNOMED CT: Radial styloid tenosynovitis (21794005); de Quervain's disease (21794005)
 
Monarch Initiative: MONDO:0006721

Definition

Stenosing tenosynovitis of the abductor pollicis longus and extensor pollicis brevis tendons in the first dorsal wrist compartment. The presenting symptoms are usually pain and tenderness at the radial styloid. The cause is almost always related to overuse injury or is associated with rheumatoid arthritis. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDe Quervain disease

Professional guidelines

PubMed

Physical modalities for the conservative treatment of wrist and hand's tenosynovitis: A systematic review.
Ferrara PE, Codazza S, Cerulli S, Maccauro G, Ferriero G, Ronconi G
Semin Arthritis Rheum 2020 Dec;50(6):1280-1290. Epub 2020 Aug 29 doi: 10.1016/j.semarthrit.2020.08.006. PMID: 33065423
Conservative Management of de Quervain Stenosing Tenosynovitis: Review and Presentation of Treatment Algorithm.
Abi-Rafeh J, Kazan R, Safran T, Thibaudeau S
Plast Reconstr Surg 2020 Jul;146(1):105-126. doi: 10.1097/PRS.0000000000006901. PMID: 32590652
Hand and Wrist Injuries in Golfers and Their Treatment.
Woo SH, Lee YK, Kim JM, Cheon HJ, Chung WH
Hand Clin 2017 Feb;33(1):81-96. doi: 10.1016/j.hcl.2016.08.012. PMID: 27886842

Recent clinical studies

Etiology

The effects of taping on de Quervain's disease: A systematic review and meta-analysis.
Drapeza RC Jr, Navasca SB, Dones V 3rd, Rimando CR
J Bodyw Mov Ther 2022 Oct;32:218-227. Epub 2022 May 27 doi: 10.1016/j.jbmt.2022.05.004. PMID: 36180153
Common Hand Conditions: A Review.
Currie KB, Tadisina KK, Mackinnon SE
JAMA 2022 Jun 28;327(24):2434-2445. doi: 10.1001/jama.2022.8481. PMID: 35762992
Paraffin bath therapy in De Quervain's tenosynovitis: a single-blind randomized controlled trial.
Karlıbel İA, Aksoy MK, Alkan A
Int J Biometeorol 2021 Aug;65(8):1391-1398. Epub 2021 Mar 6 doi: 10.1007/s00484-021-02111-2. PMID: 33675398
Physical modalities for the conservative treatment of wrist and hand's tenosynovitis: A systematic review.
Ferrara PE, Codazza S, Cerulli S, Maccauro G, Ferriero G, Ronconi G
Semin Arthritis Rheum 2020 Dec;50(6):1280-1290. Epub 2020 Aug 29 doi: 10.1016/j.semarthrit.2020.08.006. PMID: 33065423
Hand therapy versus corticosteroid injections in the treatment of de Quervain's disease: A systematic review and meta-analysis.
Cavaleri R, Schabrun SM, Te M, Chipchase LS
J Hand Ther 2016 Jan-Mar;29(1):3-11. Epub 2015 Nov 6 doi: 10.1016/j.jht.2015.10.004. PMID: 26705671

Diagnosis

Common Hand Conditions: A Review.
Currie KB, Tadisina KK, Mackinnon SE
JAMA 2022 Jun 28;327(24):2434-2445. doi: 10.1001/jama.2022.8481. PMID: 35762992
De Quervain tenosynovitis.
Caruthers LB
JAAPA 2020 Jul;33(7):49-50. doi: 10.1097/01.JAA.0000668844.44726.68. PMID: 32590534
'The side of my wrist hurts': De Quervain's tenosynovitis.
Allbrook V
Aust J Gen Pract 2019 Nov;48(11):753-756. doi: 10.31128/AJGP-07-19-5018. PMID: 31722458
Tendinopathies of the Hand and Wrist.
Adams JE, Habbu R
J Am Acad Orthop Surg 2015 Dec;23(12):741-50. Epub 2015 Oct 28 doi: 10.5435/JAAOS-D-14-00216. PMID: 26510626
De quervain tenosynovitis of the wrist.
Ilyas AM, Ast M, Schaffer AA, Thoder J
J Am Acad Orthop Surg 2007 Dec;15(12):757-64. doi: 10.5435/00124635-200712000-00009. PMID: 18063716

Therapy

The effects of taping on de Quervain's disease: A systematic review and meta-analysis.
Drapeza RC Jr, Navasca SB, Dones V 3rd, Rimando CR
J Bodyw Mov Ther 2022 Oct;32:218-227. Epub 2022 May 27 doi: 10.1016/j.jbmt.2022.05.004. PMID: 36180153
Common Hand Conditions: A Review.
Currie KB, Tadisina KK, Mackinnon SE
JAMA 2022 Jun 28;327(24):2434-2445. doi: 10.1001/jama.2022.8481. PMID: 35762992
Paraffin bath therapy in De Quervain's tenosynovitis: a single-blind randomized controlled trial.
Karlıbel İA, Aksoy MK, Alkan A
Int J Biometeorol 2021 Aug;65(8):1391-1398. Epub 2021 Mar 6 doi: 10.1007/s00484-021-02111-2. PMID: 33675398
'The side of my wrist hurts': De Quervain's tenosynovitis.
Allbrook V
Aust J Gen Pract 2019 Nov;48(11):753-756. doi: 10.31128/AJGP-07-19-5018. PMID: 31722458
Hand therapy versus corticosteroid injections in the treatment of de Quervain's disease: A systematic review and meta-analysis.
Cavaleri R, Schabrun SM, Te M, Chipchase LS
J Hand Ther 2016 Jan-Mar;29(1):3-11. Epub 2015 Nov 6 doi: 10.1016/j.jht.2015.10.004. PMID: 26705671

Prognosis

Utility of Ultrasonography and Significance of Surgical Anatomy in the Management of de Quervain Disease: A Systematic Review and Meta-Analysis.
Abi-Rafeh J, Mojtahed Jaberi M, Kazan R, Alabdulkarim A, Boily M, Thibaudeau S
Plast Reconstr Surg 2022 Feb 1;149(2):420-434. doi: 10.1097/PRS.0000000000008792. PMID: 35077418
De Quervain Tenosynovitis: An Evaluation of the Epidemiology and Utility of Multiple Injections Using a National Database.
Hassan K, Sohn A, Shi L, Lee M, Wolf JM
J Hand Surg Am 2022 Mar;47(3):284.e1-284.e6. Epub 2021 Jun 17 doi: 10.1016/j.jhsa.2021.04.018. PMID: 34147317
Relationship between the incidence of de Quervain's disease among teenagers and mobile gaming.
Ma T, Song L, Ning S, Wang H, Zhang G, Wu Z
Int Orthop 2019 Nov;43(11):2587-2592. Epub 2019 Aug 28 doi: 10.1007/s00264-019-04389-9. PMID: 31463625
Correlation Between IL-20 and De Quervain's Disease Severity.
Kuo YL, Jou IM, Wang PH, Yang TH, Shen CJ, Hsu CC
Ann Plast Surg 2019 Jan;82(1S Suppl 1):S6-S12. doi: 10.1097/SAP.0000000000001701. PMID: 30540601
Patient- and Disease-Specific Factors Associated With Operative Management of de Quervain Tendinopathy.
Kazmers NH, Liu TC, Gordon JA, Bozentka DJ, Steinberg DR, Gray BL
J Hand Surg Am 2017 Nov;42(11):931.e1-931.e7. Epub 2017 Sep 7 doi: 10.1016/j.jhsa.2017.07.017. PMID: 28888574

Clinical prediction guides

The effects of taping on de Quervain's disease: A systematic review and meta-analysis.
Drapeza RC Jr, Navasca SB, Dones V 3rd, Rimando CR
J Bodyw Mov Ther 2022 Oct;32:218-227. Epub 2022 May 27 doi: 10.1016/j.jbmt.2022.05.004. PMID: 36180153
Common Hand Conditions: A Review.
Currie KB, Tadisina KK, Mackinnon SE
JAMA 2022 Jun 28;327(24):2434-2445. doi: 10.1001/jama.2022.8481. PMID: 35762992
The association between smartphone addiction and thumb/wrist pain: A cross-sectional study.
Baabdullah A, Bokhary D, Kabli Y, Saggaf O, Daiwali M, Hamdi A
Medicine (Baltimore) 2020 Mar;99(10):e19124. doi: 10.1097/MD.0000000000019124. PMID: 32150053Free PMC Article
Correlation Between IL-20 and De Quervain's Disease Severity.
Kuo YL, Jou IM, Wang PH, Yang TH, Shen CJ, Hsu CC
Ann Plast Surg 2019 Jan;82(1S Suppl 1):S6-S12. doi: 10.1097/SAP.0000000000001701. PMID: 30540601
Patient- and Disease-Specific Factors Associated With Operative Management of de Quervain Tendinopathy.
Kazmers NH, Liu TC, Gordon JA, Bozentka DJ, Steinberg DR, Gray BL
J Hand Surg Am 2017 Nov;42(11):931.e1-931.e7. Epub 2017 Sep 7 doi: 10.1016/j.jhsa.2017.07.017. PMID: 28888574

Recent systematic reviews

The effects of taping on de Quervain's disease: A systematic review and meta-analysis.
Drapeza RC Jr, Navasca SB, Dones V 3rd, Rimando CR
J Bodyw Mov Ther 2022 Oct;32:218-227. Epub 2022 May 27 doi: 10.1016/j.jbmt.2022.05.004. PMID: 36180153
Physical modalities for the conservative treatment of wrist and hand's tenosynovitis: A systematic review.
Ferrara PE, Codazza S, Cerulli S, Maccauro G, Ferriero G, Ronconi G
Semin Arthritis Rheum 2020 Dec;50(6):1280-1290. Epub 2020 Aug 29 doi: 10.1016/j.semarthrit.2020.08.006. PMID: 33065423
Effectiveness of Conservative, Surgical, and Postsurgical Interventions for Trigger Finger, Dupuytren Disease, and De Quervain Disease: A Systematic Review.
Huisstede BM, Gladdines S, Randsdorp MS, Koes BW
Arch Phys Med Rehabil 2018 Aug;99(8):1635-1649.e21. Epub 2017 Aug 30 doi: 10.1016/j.apmr.2017.07.014. PMID: 28860097
Hand therapy versus corticosteroid injections in the treatment of de Quervain's disease: A systematic review and meta-analysis.
Cavaleri R, Schabrun SM, Te M, Chipchase LS
J Hand Ther 2016 Jan-Mar;29(1):3-11. Epub 2015 Nov 6 doi: 10.1016/j.jht.2015.10.004. PMID: 26705671
Systematic review and meta-analysis on steroid injection therapy for de Quervain's tenosynovitis in adults.
Ashraf MO, Devadoss VG
Eur J Orthop Surg Traumatol 2014 Feb;24(2):149-57. Epub 2013 Jan 22 doi: 10.1007/s00590-012-1164-z. PMID: 23412309

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...