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Thought blocking

MedGen UID:
1050573
•Concept ID:
CN375705
•
Finding
Synonym: Thought-blocking
 
HPO: HP:5200227

Definition

The interruption of speech causes an abnormal period of silence, followed by a sudden switch to an unrelated topic. Some may describe the experience as an abrupt emptying of the mind or the belief that an external force removed their thoughts from their head. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVThought blocking

Professional guidelines

PubMed

Other forms of treatment for anxiety.
Pretorius HW
S Afr Med J 1985 Oct 26;Suppl:30-2. PMID: 2865824

Recent clinical studies

Etiology

Cerebral glucose hypometabolism and hypoperfusion of cingulate gyrus: an imaging biomarker of autoimmune encephalitis with psychiatric symptoms.
Sun Y, Li G, Liu X, Zhao X, Ren J, Ren G, Liu Y, Ai L, Wang Q
J Neurol 2024 Mar;271(3):1247-1255. Epub 2023 Nov 9 doi: 10.1007/s00415-023-12051-z. PMID: 37945763Free PMC Article
"You Just Come to School, If You Made It, Its Grace": Young Black Women's Experiences of Violence in Utilizing Public "Minibus Taxi" Transport in Johannesburg, South Africa.
Eagle G, Kwele K
J Interpers Violence 2021 Aug;36(15-16):NP8034-NP8055. Epub 2019 Apr 9 doi: 10.1177/0886260519840395. PMID: 30964387
Brain functional connectivity and the pathophysiology of schizophrenia.
Angelopoulos E
Psychiatriki 2014 Apr-Jun;25(2):91-4. PMID: 25035177

Diagnosis

Thought Blocking as a Manifestation of Catatonia: A Case Report.
Elmarasi O, Abdelhady S, Mahgoub Y
J Nerv Ment Dis 2024 Feb 1;212(2):120-121. doi: 10.1097/NMD.0000000000001727. PMID: 38290105
Indication of Disrupted Temporal Structure in the Case of Thought Blocks in Schizophrenia: The Role of the Metastable Balance.
Koutsoukos E, Angelopoulos E
Behav Neurol 2018;2018:4031207. Epub 2018 Sep 2 doi: 10.1155/2018/4031207. PMID: 30245749Free PMC Article
Disorders of thought are severe mood disorders: the selective attention defect in mania challenges the Kraepelinian dichotomy a review.
Raymond Lake C
Schizophr Bull 2008 Jan;34(1):109-17. Epub 2007 May 21 doi: 10.1093/schbul/sbm035. PMID: 17515440Free PMC Article
First-episode psychosis in the military: a comparative study of prodromal symptoms.
Tan HY, Ang YG
Aust N Z J Psychiatry 2001 Aug;35(4):512-9. doi: 10.1046/j.1440-1614.2001.00912.x. PMID: 11531734
A rating scale for psychotic symptoms (RSPS): part II: subscale 2: distraction symptoms (catatonia and passivity experiences subscale 3: delusions and semi-structured interview (SSCI-RSPS).
Chouinard G, Miller R
Schizophr Res 1999 Aug 17;38(2-3):123-50. doi: 10.1016/s0920-9964(99)00013-4. PMID: 10463459

Therapy

Thought Blocking as a Manifestation of Catatonia: A Case Report.
Elmarasi O, Abdelhady S, Mahgoub Y
J Nerv Ment Dis 2024 Feb 1;212(2):120-121. doi: 10.1097/NMD.0000000000001727. PMID: 38290105
A TNF-α blocking peptide that reduces NF-κB and MAPK activity for attenuating inflammation.
Wang Y, Ye R, Fan L, Zhao X, Li L, Zheng H, Qiu Y, He X, Lu Y
Bioorg Med Chem 2023 Sep 7;92:117420. Epub 2023 Jul 20 doi: 10.1016/j.bmc.2023.117420. PMID: 37573821
Indication of Disrupted Temporal Structure in the Case of Thought Blocks in Schizophrenia: The Role of the Metastable Balance.
Koutsoukos E, Angelopoulos E
Behav Neurol 2018;2018:4031207. Epub 2018 Sep 2 doi: 10.1155/2018/4031207. PMID: 30245749Free PMC Article
Adolescent salvia substance abuse.
Singh S
Addiction 2007 May;102(5):823-4. doi: 10.1111/j.1360-0443.2007.01810.x. PMID: 17493110
Other forms of treatment for anxiety.
Pretorius HW
S Afr Med J 1985 Oct 26;Suppl:30-2. PMID: 2865824

Prognosis

Thought Blocking as a Manifestation of Catatonia: A Case Report.
Elmarasi O, Abdelhady S, Mahgoub Y
J Nerv Ment Dis 2024 Feb 1;212(2):120-121. doi: 10.1097/NMD.0000000000001727. PMID: 38290105
Cerebral glucose hypometabolism and hypoperfusion of cingulate gyrus: an imaging biomarker of autoimmune encephalitis with psychiatric symptoms.
Sun Y, Li G, Liu X, Zhao X, Ren J, Ren G, Liu Y, Ai L, Wang Q
J Neurol 2024 Mar;271(3):1247-1255. Epub 2023 Nov 9 doi: 10.1007/s00415-023-12051-z. PMID: 37945763Free PMC Article
First-episode psychosis in the military: a comparative study of prodromal symptoms.
Tan HY, Ang YG
Aust N Z J Psychiatry 2001 Aug;35(4):512-9. doi: 10.1046/j.1440-1614.2001.00912.x. PMID: 11531734

Clinical prediction guides

Cerebral glucose hypometabolism and hypoperfusion of cingulate gyrus: an imaging biomarker of autoimmune encephalitis with psychiatric symptoms.
Sun Y, Li G, Liu X, Zhao X, Ren J, Ren G, Liu Y, Ai L, Wang Q
J Neurol 2024 Mar;271(3):1247-1255. Epub 2023 Nov 9 doi: 10.1007/s00415-023-12051-z. PMID: 37945763Free PMC Article
Indication of Disrupted Temporal Structure in the Case of Thought Blocks in Schizophrenia: The Role of the Metastable Balance.
Koutsoukos E, Angelopoulos E
Behav Neurol 2018;2018:4031207. Epub 2018 Sep 2 doi: 10.1155/2018/4031207. PMID: 30245749Free PMC Article
Brain functional connectivity and the pathophysiology of schizophrenia.
Angelopoulos E
Psychiatriki 2014 Apr-Jun;25(2):91-4. PMID: 25035177
Disorders of thought are severe mood disorders: the selective attention defect in mania challenges the Kraepelinian dichotomy a review.
Raymond Lake C
Schizophr Bull 2008 Jan;34(1):109-17. Epub 2007 May 21 doi: 10.1093/schbul/sbm035. PMID: 17515440Free PMC Article

Supplemental Content

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