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Addictive cannabis use

MedGen UID:
1051887
•Concept ID:
CN375770
•
Finding
Synonyms: Addictive marijuana use; Cannabis addiction; Marijuana addiction
 
HPO: HP:5200341

Definition

A persistent and compulsive need to use cannabis, despite negative consequences. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAddictive cannabis use

Professional guidelines

PubMed

Clinical management of cannabis withdrawal.
Connor JP, Stjepanović D, Budney AJ, Le Foll B, Hall WD
Addiction 2022 Jul;117(7):2075-2095. Epub 2022 Jan 10 doi: 10.1111/add.15743. PMID: 34791767Free PMC Article
Cannabidiol: A Potential New Alternative for the Treatment of Anxiety, Depression, and Psychotic Disorders.
García-Gutiérrez MS, Navarrete F, Gasparyan A, Austrich-Olivares A, Sala F, Manzanares J
Biomolecules 2020 Nov 19;10(11) doi: 10.3390/biom10111575. PMID: 33228239Free PMC Article
Cannabinoids for the treatment of mental disorders and symptoms of mental disorders: a systematic review and meta-analysis.
Black N, Stockings E, Campbell G, Tran LT, Zagic D, Hall WD, Farrell M, Degenhardt L
Lancet Psychiatry 2019 Dec;6(12):995-1010. Epub 2019 Oct 28 doi: 10.1016/S2215-0366(19)30401-8. PMID: 31672337Free PMC Article

Recent clinical studies

Etiology

Adverse Effects of Recreational and Medical Cannabis.
Urits I, Charipova K, Gress K, Li N, Berger AA, Cornett EM, Kassem H, Ngo AL, Kaye AD, Viswanath O
Psychopharmacol Bull 2021 Jan 12;51(1):94-109. PMID: 33897066Free PMC Article
Cannabis use and cannabis use disorder.
Connor JP, Stjepanović D, Le Foll B, Hoch E, Budney AJ, Hall WD
Nat Rev Dis Primers 2021 Feb 25;7(1):16. doi: 10.1038/s41572-021-00247-4. PMID: 33627670Free PMC Article
The Neuroscience of Drug Reward and Addiction.
Volkow ND, Michaelides M, Baler R
Physiol Rev 2019 Oct 1;99(4):2115-2140. doi: 10.1152/physrev.00014.2018. PMID: 31507244Free PMC Article
Effects of Cannabis Use on Human Behavior, Including Cognition, Motivation, and Psychosis: A Review.
Volkow ND, Swanson JM, Evins AE, DeLisi LE, Meier MH, Gonzalez R, Bloomfield MA, Curran HV, Baler R
JAMA Psychiatry 2016 Mar;73(3):292-7. doi: 10.1001/jamapsychiatry.2015.3278. PMID: 26842658
Acute and long-term effects of cannabis use: a review.
Karila L, Roux P, Rolland B, Benyamina A, Reynaud M, Aubin HJ, Lançon C
Curr Pharm Des 2014;20(25):4112-8. doi: 10.2174/13816128113199990620. PMID: 24001294

Diagnosis

Canadian Network for Mood and Anxiety Treatments (CANMAT) Task Force Report: A Systematic Review and Recommendations of Cannabis use in Bipolar Disorder and Major Depressive Disorder.
Tourjman SV, Buck G, Jutras-Aswad D, Khullar A, McInerney S, Saraf G, Pinto JV, Potvin S, Poulin MJ, Frey BN, Kennedy SH, Lam RW, MacQueen G, Milev R, Parikh SV, Ravindran A, McIntyre RS, Schaffer A, Taylor VH, van Ameringen M, Yatham LN, Beaulieu S
Can J Psychiatry 2023 May;68(5):299-311. Epub 2022 Jun 16 doi: 10.1177/07067437221099769. PMID: 35711159Free PMC Article
Substance-Use Disorders in Children and Adolescents.
Thomasius R, Paschke K, Arnaud N
Dtsch Arztebl Int 2022 Jun 24;119(25):440-450. doi: 10.3238/arztebl.m2022.0122. PMID: 35635442Free PMC Article
Clinical management of cannabis withdrawal.
Connor JP, Stjepanović D, Budney AJ, Le Foll B, Hall WD
Addiction 2022 Jul;117(7):2075-2095. Epub 2022 Jan 10 doi: 10.1111/add.15743. PMID: 34791767Free PMC Article
Bipolar Disorder and Comorbid Use of Illicit Substances.
Preuss UW, Schaefer M, Born C, Grunze H
Medicina (Kaunas) 2021 Nov 17;57(11) doi: 10.3390/medicina57111256. PMID: 34833474Free PMC Article
The dopamine theory of addiction: 40 years of highs and lows.
Nutt DJ, Lingford-Hughes A, Erritzoe D, Stokes PR
Nat Rev Neurosci 2015 May;16(5):305-12. Epub 2015 Apr 15 doi: 10.1038/nrn3939. PMID: 25873042

Therapy

Adverse Effects of Recreational and Medical Cannabis.
Urits I, Charipova K, Gress K, Li N, Berger AA, Cornett EM, Kassem H, Ngo AL, Kaye AD, Viswanath O
Psychopharmacol Bull 2021 Jan 12;51(1):94-109. PMID: 33897066Free PMC Article
Cannabis use and cannabis use disorder.
Connor JP, Stjepanović D, Le Foll B, Hoch E, Budney AJ, Hall WD
Nat Rev Dis Primers 2021 Feb 25;7(1):16. doi: 10.1038/s41572-021-00247-4. PMID: 33627670Free PMC Article
Cannabis Addiction and the Brain: a Review.
Zehra A, Burns J, Liu CK, Manza P, Wiers CE, Volkow ND, Wang GJ
J Neuroimmune Pharmacol 2018 Dec;13(4):438-452. Epub 2018 Mar 19 doi: 10.1007/s11481-018-9782-9. PMID: 29556883Free PMC Article
Effects of Cannabis Use on Human Behavior, Including Cognition, Motivation, and Psychosis: A Review.
Volkow ND, Swanson JM, Evins AE, DeLisi LE, Meier MH, Gonzalez R, Bloomfield MA, Curran HV, Baler R
JAMA Psychiatry 2016 Mar;73(3):292-7. doi: 10.1001/jamapsychiatry.2015.3278. PMID: 26842658
Acute and long-term effects of cannabis use: a review.
Karila L, Roux P, Rolland B, Benyamina A, Reynaud M, Aubin HJ, Lançon C
Curr Pharm Des 2014;20(25):4112-8. doi: 10.2174/13816128113199990620. PMID: 24001294

Prognosis

Canadian Network for Mood and Anxiety Treatments (CANMAT) Task Force Report: A Systematic Review and Recommendations of Cannabis use in Bipolar Disorder and Major Depressive Disorder.
Tourjman SV, Buck G, Jutras-Aswad D, Khullar A, McInerney S, Saraf G, Pinto JV, Potvin S, Poulin MJ, Frey BN, Kennedy SH, Lam RW, MacQueen G, Milev R, Parikh SV, Ravindran A, McIntyre RS, Schaffer A, Taylor VH, van Ameringen M, Yatham LN, Beaulieu S
Can J Psychiatry 2023 May;68(5):299-311. Epub 2022 Jun 16 doi: 10.1177/07067437221099769. PMID: 35711159Free PMC Article
Substance-Use Disorders in Children and Adolescents.
Thomasius R, Paschke K, Arnaud N
Dtsch Arztebl Int 2022 Jun 24;119(25):440-450. doi: 10.3238/arztebl.m2022.0122. PMID: 35635442Free PMC Article
Clinical management of cannabis withdrawal.
Connor JP, Stjepanović D, Budney AJ, Le Foll B, Hall WD
Addiction 2022 Jul;117(7):2075-2095. Epub 2022 Jan 10 doi: 10.1111/add.15743. PMID: 34791767Free PMC Article
Cannabis and Depression.
Feingold D, Weinstein A
Adv Exp Med Biol 2021;1264:67-80. doi: 10.1007/978-3-030-57369-0_5. PMID: 33332004
Global statistics on alcohol, tobacco and illicit drug use: 2017 status report.
Peacock A, Leung J, Larney S, Colledge S, Hickman M, Rehm J, Giovino GA, West R, Hall W, Griffiths P, Ali R, Gowing L, Marsden J, Ferrari AJ, Grebely J, Farrell M, Degenhardt L
Addiction 2018 Oct;113(10):1905-1926. Epub 2018 Jun 4 doi: 10.1111/add.14234. PMID: 29749059

Clinical prediction guides

Illegal drugs and periodontal conditions.
Quaranta A, D'Isidoro O, Piattelli A, Hui WL, Perrotti V
Periodontol 2000 2022 Oct;90(1):62-87. doi: 10.1111/prd.12450. PMID: 36183328Free PMC Article
Association of cannabis potency with mental ill health and addiction: a systematic review.
Petrilli K, Ofori S, Hines L, Taylor G, Adams S, Freeman TP
Lancet Psychiatry 2022 Sep;9(9):736-750. Epub 2022 Jul 25 doi: 10.1016/S2215-0366(22)00161-4. PMID: 35901795
Combined use of alcohol and cannabis: Introduction to the special issue.
Linden-Carmichael AN, Wardell JD
Psychol Addict Behav 2021 Sep;35(6):621-627. doi: 10.1037/adb0000772. PMID: 34591513Free PMC Article
Cannabis and Depression.
Feingold D, Weinstein A
Adv Exp Med Biol 2021;1264:67-80. doi: 10.1007/978-3-030-57369-0_5. PMID: 33332004
The dopamine theory of addiction: 40 years of highs and lows.
Nutt DJ, Lingford-Hughes A, Erritzoe D, Stokes PR
Nat Rev Neurosci 2015 May;16(5):305-12. Epub 2015 Apr 15 doi: 10.1038/nrn3939. PMID: 25873042

Recent systematic reviews

Association of cannabis potency with mental ill health and addiction: a systematic review.
Petrilli K, Ofori S, Hines L, Taylor G, Adams S, Freeman TP
Lancet Psychiatry 2022 Sep;9(9):736-750. Epub 2022 Jul 25 doi: 10.1016/S2215-0366(22)00161-4. PMID: 35901795
Oral Administration of Cannabis and Δ-9-tetrahydrocannabinol (THC) Preparations: A Systematic Review.
Poyatos L, Pérez-Acevedo AP, Papaseit E, Pérez-Mañá C, Martin S, Hladun O, Siles A, Torrens M, Busardo FP, Farré M
Medicina (Kaunas) 2020 Jun 23;56(6) doi: 10.3390/medicina56060309. PMID: 32585912Free PMC Article
Cannabinoids for the treatment of mental disorders and symptoms of mental disorders: a systematic review and meta-analysis.
Black N, Stockings E, Campbell G, Tran LT, Zagic D, Hall WD, Farrell M, Degenhardt L
Lancet Psychiatry 2019 Dec;6(12):995-1010. Epub 2019 Oct 28 doi: 10.1016/S2215-0366(19)30401-8. PMID: 31672337Free PMC Article
Prevention, early intervention, harm reduction, and treatment of substance use in young people.
Stockings E, Hall WD, Lynskey M, Morley KI, Reavley N, Strang J, Patton G, Degenhardt L
Lancet Psychiatry 2016 Mar;3(3):280-96. Epub 2016 Feb 18 doi: 10.1016/S2215-0366(16)00002-X. PMID: 26905481
Clinical trials of N-acetylcysteine in psychiatry and neurology: A systematic review.
Deepmala, Slattery J, Kumar N, Delhey L, Berk M, Dean O, Spielholz C, Frye R
Neurosci Biobehav Rev 2015 Aug;55:294-321. Epub 2015 May 6 doi: 10.1016/j.neubiorev.2015.04.015. PMID: 25957927

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