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Anti-factor XI antibody positivity

MedGen UID:: 1052361
•Concept ID:: CN377328
•: Finding

Synonym:	Anti-FXI antibody positivity

HPO:	HP:6000497

Definition

The presence of an antibody in the blood circulation that is directed against factor XI. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAnti-factor XI antibody positivity

Phenotypic abnormality
- Abnormality of the immune system
  - Abnormality of immune system physiology
    - Autoimmunity
      - Autoimmune antibody positivity
        Anti-coagulation factor antibody positivity
        Anti-factor XI antibody positivity

Recent clinical studies

Therapy

Microparticles from patients with multiple organ dysfunction syndrome and sepsis support coagulation through multiple mechanisms.

Joop K, Berckmans RJ, Nieuwland R, Berkhout J, Romijn FP, Hack CE, Sturk A
Thromb Haemost 2001 May;85(5):810-20. PMID: 11372673

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ClinicalTrials.gov

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