U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Elevated blood mercury concentration

MedGen UID:
1052480
•Concept ID:
CN377045
•
Finding
HPO: HP:6000443

Definition

The concentration of mercury in the blood is above the upper limit of a guidance value for total blood mercury concentrations that implies possible injurious effects. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVElevated blood mercury concentration

Professional guidelines

PubMed

Artisanal and small-scale gold mining: A cross-sectional assessment of occupational mercury exposure and exposure risk factors in Kadoma and Shurugwi, Zimbabwe.
Mambrey V, Rakete S, Tobollik M, Shoko D, Moyo D, Schutzmeier P, Steckling-Muschack N, Muteti-Fana S, Bose-O'Reilly S
Environ Res 2020 May;184:109379. Epub 2020 Mar 11 doi: 10.1016/j.envres.2020.109379. PMID: 32197122
Human health risk assessment based on trace metals in suspended air particulates, surface dust, and floor dust from e-waste recycling workshops in Hong Kong, China.
Lau WK, Liang P, Man YB, Chung SS, Wong MH
Environ Sci Pollut Res Int 2014 Mar;21(5):3813-25. Epub 2013 Nov 28 doi: 10.1007/s11356-013-2372-8. PMID: 24288065

Recent clinical studies

Etiology

Association of Blood Heavy Metal Levels and Renal Function in Korean Adults.
Park Y, Lee SJ
Int J Environ Res Public Health 2022 May 29;19(11) doi: 10.3390/ijerph19116646. PMID: 35682230Free PMC Article
Normal concentration range of blood mercury and bone mineral density: a cross-sectional study of National Health and Nutrition Examination Survey (NHANES) 2005-2010.
Tang Y, Yi Q, Wang S, Xia Y, Geng B
Environ Sci Pollut Res Int 2022 Jan;29(5):7743-7757. Epub 2021 Sep 3 doi: 10.1007/s11356-021-16162-w. PMID: 34480303
A Review of Biomarkers Used for Assessing Human Exposure to Metals from E-Waste.
Arain AL, Neitzel RL
Int J Environ Res Public Health 2019 May 21;16(10) doi: 10.3390/ijerph16101802. PMID: 31117209Free PMC Article
Multiple metal exposures and metabolic syndrome: A cross-sectional analysis of the National Health and Nutrition Examination Survey 2011-2014.
Bulka CM, Persky VW, Daviglus ML, Durazo-Arvizu RA, Argos M
Environ Res 2019 Jan;168:397-405. Epub 2018 Oct 24 doi: 10.1016/j.envres.2018.10.022. PMID: 30388496Free PMC Article
Impact of heavy metals on the female reproductive system.
Rzymski P, Tomczyk K, Rzymski P, Poniedziałek B, Opala T, Wilczak M
Ann Agric Environ Med 2015;22(2):259-64. doi: 10.5604/12321966.1152077. PMID: 26094520

Diagnosis

Mercury and Alzheimer's Disease: Hg(II) Ions Display Specific Binding to the Amyloid-β Peptide and Hinder Its Fibrillization.
Wallin C, Friedemann M, Sholts SB, Noormägi A, Svantesson T, Jarvet J, Roos PM, Palumaa P, Gräslund A, Wärmländer SKTS
Biomolecules 2019 Dec 27;10(1) doi: 10.3390/biom10010044. PMID: 31892131Free PMC Article
Signs and symptoms of mercury-exposed gold miners.
Bose-O'Reilly S, Bernaudat L, Siebert U, Roider G, Nowak D, Drasch G
Int J Occup Med Environ Health 2017 Mar 30;30(2):249-269. Epub 2017 Mar 22 doi: 10.13075/ijomeh.1896.00715. PMID: 28366955
Inorganic mercury poisoning associated with skin-lightening cosmetic products.
Chan TY
Clin Toxicol (Phila) 2011 Dec;49(10):886-91. Epub 2011 Nov 9 doi: 10.3109/15563650.2011.626425. PMID: 22070559
Interpreting mercury in blood and urine of individual patients.
Nuttall KL
Ann Clin Lab Sci 2004 Summer;34(3):235-50. PMID: 15487698
Elemental mercurial poisoning.
Hohage H, Otte B, Westermann G, Witta J, Welling U, Zidek W, Heidenreich S
South Med J 1997 Oct;90(10):1033-6. doi: 10.1097/00007611-199710000-00012. PMID: 9347816

Therapy

Prenatal exposure to mercury and longitudinally assessed fetal growth: Relation and effect modifiers.
Ballester F, Iñiguez C, Murcia M, Guxens M, Basterretxea M, Rebagliato M, Vioque J, Lertxundi A, Fernandez-Somoano A, Tardon A, Sunyer J, Llop S
Environ Res 2018 Jan;160:97-106. Epub 2017 Sep 30 doi: 10.1016/j.envres.2017.09.018. PMID: 28968527
Methyl mercury, but not inorganic mercury, associated with higher blood pressure during pregnancy.
Wells EM, Herbstman JB, Lin YH, Hibbeln JR, Halden RU, Witter FR, Goldman LR
Environ Res 2017 Apr;154:247-252. Epub 2017 Jan 18 doi: 10.1016/j.envres.2017.01.013. PMID: 28110211Free PMC Article
Mercury, lead, and cadmium in umbilical cord blood.
King E, Shih G, Ratnapradipa D, Quilliam DN, Morton J, Magee SR
J Environ Health 2013 Jan-Feb;75(6):38-43. PMID: 23397648
Inorganic mercury poisoning associated with skin-lightening cosmetic products.
Chan TY
Clin Toxicol (Phila) 2011 Dec;49(10):886-91. Epub 2011 Nov 9 doi: 10.3109/15563650.2011.626425. PMID: 22070559
Elemental mercurial poisoning.
Hohage H, Otte B, Westermann G, Witta J, Welling U, Zidek W, Heidenreich S
South Med J 1997 Oct;90(10):1033-6. doi: 10.1097/00007611-199710000-00012. PMID: 9347816

Prognosis

Exposure to mercury among Spanish adolescents: Eleven years of follow-up.
López-González U, Riutort-Mayol G, Soler-Blasco R, Lozano M, Murcia M, Vioque J, Iriarte G, Ballester F, Llop S
Environ Res 2023 Aug 15;231(Pt 2):116204. Epub 2023 May 20 doi: 10.1016/j.envres.2023.116204. PMID: 37211180
Low-level exposure to lead, mercury, arsenic, and cadmium, and blood pressure among 8-17-year-old participants of the 2009-2016 National Health and Nutrition Examination Survey.
Desai G, Niu Z, Luo W, Frndak S, Shaver AL, Kordas K
Environ Res 2021 Jun;197:111086. Epub 2021 Mar 27 doi: 10.1016/j.envres.2021.111086. PMID: 33781774Free PMC Article
Biomonitoring of mercury and persistent organic pollutants in Michigan urban anglers and association with fish consumption.
Wattigney WA, Irvin-Barnwell E, Li Z, Ragin-Wilson A
Int J Hyg Environ Health 2019 Jul;222(6):936-944. Epub 2019 Jun 27 doi: 10.1016/j.ijheh.2019.06.007. PMID: 31257185Free PMC Article
Relationship between selenium, lead, and mercury in red blood cells of Saudi autistic children.
El-Ansary A, Bjørklund G, Tinkov AA, Skalny AV, Al Dera H
Metab Brain Dis 2017 Aug;32(4):1073-1080. Epub 2017 Mar 21 doi: 10.1007/s11011-017-9996-1. PMID: 28326463
Blood mercury concentrations in CHARGE Study children with and without autism.
Hertz-Picciotto I, Green PG, Delwiche L, Hansen R, Walker C, Pessah IN
Environ Health Perspect 2010 Jan;118(1):161-6. doi: 10.1289/ehp.0900736. PMID: 20056569Free PMC Article

Clinical prediction guides

Normal concentration range of blood mercury and bone mineral density: a cross-sectional study of National Health and Nutrition Examination Survey (NHANES) 2005-2010.
Tang Y, Yi Q, Wang S, Xia Y, Geng B
Environ Sci Pollut Res Int 2022 Jan;29(5):7743-7757. Epub 2021 Sep 3 doi: 10.1007/s11356-021-16162-w. PMID: 34480303
Cadmium, lead and mercury in the blood of psoriatic and vitiligo patients and their possible associations with dietary habits.
Wacewicz-Muczyńska M, Socha K, Soroczyńska J, Niczyporuk M, Borawska MH
Sci Total Environ 2021 Feb 25;757:143967. Epub 2020 Dec 3 doi: 10.1016/j.scitotenv.2020.143967. PMID: 33302005
A Review of Biomarkers Used for Assessing Human Exposure to Metals from E-Waste.
Arain AL, Neitzel RL
Int J Environ Res Public Health 2019 May 21;16(10) doi: 10.3390/ijerph16101802. PMID: 31117209Free PMC Article
Multiple metal exposures and metabolic syndrome: A cross-sectional analysis of the National Health and Nutrition Examination Survey 2011-2014.
Bulka CM, Persky VW, Daviglus ML, Durazo-Arvizu RA, Argos M
Environ Res 2019 Jan;168:397-405. Epub 2018 Oct 24 doi: 10.1016/j.envres.2018.10.022. PMID: 30388496Free PMC Article
Methyl mercury, but not inorganic mercury, associated with higher blood pressure during pregnancy.
Wells EM, Herbstman JB, Lin YH, Hibbeln JR, Halden RU, Witter FR, Goldman LR
Environ Res 2017 Apr;154:247-252. Epub 2017 Jan 18 doi: 10.1016/j.envres.2017.01.013. PMID: 28110211Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...