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Rest limb pain

MedGen UID:
1052511
•Concept ID:
CN377459
•
Finding
Synonym: Critical limb ischemia
 
HPO: HP:6000627

Definition

Rest pain is a continuous unrelenting pain due to ischemia of the lower leg, beginning with or being aggravated by elevation and being relieved by sitting with legs in a dependent position or by standing. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRest limb pain

Professional guidelines

PubMed

Advanced peripheral arteriosclerosis; a physiological approach to management.
ATLAS LN
Calif Med 1954 Jun;80(6):441-4. PMID: 13160814Free PMC Article

Recent clinical studies

Etiology

The role of progressive, therapeutic exercise in the management of upper limb tendinopathies: A systematic review and meta-analysis.
Ortega-Castillo M, Cuesta-Vargas A, Luque-Teba A, Trinidad-Fernández M
Musculoskelet Sci Pract 2022 Dec;62:102645. Epub 2022 Aug 8 doi: 10.1016/j.msksp.2022.102645. PMID: 35964498
Impact of adding scapular stabilization to postural correctional exercises on symptomatic forward head posture: a randomized controlled trial.
Abd El-Azeim AS, Mahmoud AG, Mohamed MT, El-Khateeb YS
Eur J Phys Rehabil Med 2022 Oct;58(5):757-766. Epub 2022 Jun 8 doi: 10.23736/S1973-9087.22.07361-0. PMID: 35673945Free PMC Article
Interscalene Brachial Plexus Block with Liposomal Bupivacaine versus Standard Bupivacaine with Perineural Dexamethasone: A Noninferiority Trial.
Kim DH, Liu J, Beathe JC, Lin Y, Wetmore DS, Kim SJ, Haskins SC, Garvin S, Oxendine JA, Ho MC, Allen AA, Popovic M, Gbaje E, Wu CL, Memtsoudis SG
Anesthesiology 2022 Mar 1;136(3):434-447. doi: 10.1097/ALN.0000000000004111. PMID: 35041742
Ergonomic interventions for preventing work-related musculoskeletal disorders of the upper limb and neck among office workers.
Hoe VC, Urquhart DM, Kelsall HL, Zamri EN, Sim MR
Cochrane Database Syst Rev 2018 Oct 23;10(10):CD008570. doi: 10.1002/14651858.CD008570.pub3. PMID: 30350850Free PMC Article
Stress fractures: diagnosis, treatment, and prevention.
Patel DS, Roth M, Kapil N
Am Fam Physician 2011 Jan 1;83(1):39-46. PMID: 21888126

Diagnosis

Lateral Epicondylitis/Extensor Tendon Injury.
Meunier M
Clin Sports Med 2020 Jul;39(3):657-660. doi: 10.1016/j.csm.2020.03.001. PMID: 32446581
Global Vascular Guidelines on the Management of Chronic Limb-Threatening Ischemia.
Conte MS, Bradbury AW, Kolh P, White JV, Dick F, Fitridge R, Mills JL, Ricco JB, Suresh KR, Murad MH, Aboyans V, Aksoy M, Alexandrescu VA, Armstrong D, Azuma N, Belch J, Bergoeing M, Bjorck M, Chakfé N, Cheng S, Dawson J, Debus ES, Dueck A, Duval S, Eckstein HH, Ferraresi R, Gambhir R, Gargiulo M, Geraghty P, Goode S, Gray B, Guo W, Gupta PC, Hinchliffe R, Jetty P, Komori K, Lavery L, Liang W, Lookstein R, Menard M, Misra S, Miyata T, Moneta G, Munoa Prado JA, Munoz A, Paolini JE, Patel M, Pomposelli F, Powell R, Robless P, Rogers L, Schanzer A, Schneider P, Taylor S, De Ceniga MV, Veller M, Vermassen F, Wang J, Wang S; GVG Writing Group for the Joint Guidelines of the Society for Vascular Surgery (SVS), European Society for Vascular Surgery (ESVS), and World Federation of Vascular Societies (WFVS)
Eur J Vasc Endovasc Surg 2019 Jul;58(1S):S1-S109.e33. Epub 2019 Jun 8 doi: 10.1016/j.ejvs.2019.05.006. PMID: 31182334Free PMC Article
Heel Pain: Diagnosis and Management.
Tu P
Am Fam Physician 2018 Jan 15;97(2):86-93. PMID: 29365222
Heel pain: A systematic review.
Agyekum EK, Ma K
Chin J Traumatol 2015;18(3):164-9. doi: 10.1016/j.cjtee.2015.03.002. PMID: 26643244
Stress fractures: diagnosis, treatment, and prevention.
Patel DS, Roth M, Kapil N
Am Fam Physician 2011 Jan 1;83(1):39-46. PMID: 21888126

Therapy

The role of progressive, therapeutic exercise in the management of upper limb tendinopathies: A systematic review and meta-analysis.
Ortega-Castillo M, Cuesta-Vargas A, Luque-Teba A, Trinidad-Fernández M
Musculoskelet Sci Pract 2022 Dec;62:102645. Epub 2022 Aug 8 doi: 10.1016/j.msksp.2022.102645. PMID: 35964498
Impact of adding scapular stabilization to postural correctional exercises on symptomatic forward head posture: a randomized controlled trial.
Abd El-Azeim AS, Mahmoud AG, Mohamed MT, El-Khateeb YS
Eur J Phys Rehabil Med 2022 Oct;58(5):757-766. Epub 2022 Jun 8 doi: 10.23736/S1973-9087.22.07361-0. PMID: 35673945Free PMC Article
Ergonomic interventions for preventing work-related musculoskeletal disorders of the upper limb and neck among office workers.
Hoe VC, Urquhart DM, Kelsall HL, Zamri EN, Sim MR
Cochrane Database Syst Rev 2018 Oct 23;10(10):CD008570. doi: 10.1002/14651858.CD008570.pub3. PMID: 30350850Free PMC Article
Kinesio taping reduces elbow pain during resisted wrist extension in patients with chronic lateral epicondylitis: a randomized, double-blinded, cross-over study.
Cho YT, Hsu WY, Lin LF, Lin YN
BMC Musculoskelet Disord 2018 Jun 19;19(1):193. doi: 10.1186/s12891-018-2118-3. PMID: 29921250Free PMC Article
Stress fractures: diagnosis, treatment, and prevention.
Patel DS, Roth M, Kapil N
Am Fam Physician 2011 Jan 1;83(1):39-46. PMID: 21888126

Prognosis

Comparison of extracorporeal shock wave therapy with custom foot orthotics in plantar fasciitis treatment: A prospective randomized one-year follow-up study.
Çağlar Okur S, Aydın A
J Musculoskelet Neuronal Interact 2019 Jun 1;19(2):178-186. PMID: 31186388Free PMC Article
Contemporary Management of Critical Limb Ischemia.
Thompson JR, Henke PK
Adv Surg 2018 Sep;52(1):257-274. Epub 2018 Jun 19 doi: 10.1016/j.yasu.2018.03.012. PMID: 30098617
Proximal Hamstring Tendinosis and Partial Ruptures.
Startzman AN, Fowler O, Carreira D
Orthopedics 2017 Jul 1;40(4):e574-e582. Epub 2017 Feb 14 doi: 10.3928/01477447-20170208-05. PMID: 28195608
Critical limb ischemia.
Elsayed S, Clavijo LC
Cardiol Clin 2015 Feb;33(1):37-47. doi: 10.1016/j.ccl.2014.09.008. PMID: 25439329
Critical limb ischaemia.
Minar E
Hamostaseologie 2009 Jan;29(1):102-9. PMID: 19151858

Clinical prediction guides

The role of progressive, therapeutic exercise in the management of upper limb tendinopathies: A systematic review and meta-analysis.
Ortega-Castillo M, Cuesta-Vargas A, Luque-Teba A, Trinidad-Fernández M
Musculoskelet Sci Pract 2022 Dec;62:102645. Epub 2022 Aug 8 doi: 10.1016/j.msksp.2022.102645. PMID: 35964498
Interscalene Brachial Plexus Block with Liposomal Bupivacaine versus Standard Bupivacaine with Perineural Dexamethasone: A Noninferiority Trial.
Kim DH, Liu J, Beathe JC, Lin Y, Wetmore DS, Kim SJ, Haskins SC, Garvin S, Oxendine JA, Ho MC, Allen AA, Popovic M, Gbaje E, Wu CL, Memtsoudis SG
Anesthesiology 2022 Mar 1;136(3):434-447. doi: 10.1097/ALN.0000000000004111. PMID: 35041742
Early Results of Kinesio Taping and Steroid Injections in Elbow Lateral Epicondylitis: A Randomized, Controlled Study.
Erpala F, Ozturk T, Zengin EC, Bakir U
Medicina (Kaunas) 2021 Mar 24;57(4) doi: 10.3390/medicina57040306. PMID: 33805193Free PMC Article
Effects of Vibration and Non-Vibration Foam Rolling on Recovery after Exercise with Induced Muscle Damage.
Romero-Moraleda B, González-García J, Cuéllar-Rayo Á, Balsalobre-Fernández C, Muñoz-García D, Morencos E
J Sports Sci Med 2019 Mar;18(1):172-180. Epub 2019 Feb 11 PMID: 30787665Free PMC Article
The Society for Vascular Surgery Lower Extremity Threatened Limb Classification System: risk stratification based on wound, ischemia, and foot infection (WIfI).
Mills JL Sr, Conte MS, Armstrong DG, Pomposelli FB, Schanzer A, Sidawy AN, Andros G; Society for Vascular Surgery Lower Extremity Guidelines Committee
J Vasc Surg 2014 Jan;59(1):220-34.e1-2. Epub 2013 Oct 12 doi: 10.1016/j.jvs.2013.08.003. PMID: 24126108

Recent systematic reviews

The role of progressive, therapeutic exercise in the management of upper limb tendinopathies: A systematic review and meta-analysis.
Ortega-Castillo M, Cuesta-Vargas A, Luque-Teba A, Trinidad-Fernández M
Musculoskelet Sci Pract 2022 Dec;62:102645. Epub 2022 Aug 8 doi: 10.1016/j.msksp.2022.102645. PMID: 35964498
Global vascular guidelines on the management of chronic limb-threatening ischemia.
Conte MS, Bradbury AW, Kolh P, White JV, Dick F, Fitridge R, Mills JL, Ricco JB, Suresh KR, Murad MH; GVG Writing Group
J Vasc Surg 2019 Jun;69(6S):3S-125S.e40. Epub 2019 May 28 doi: 10.1016/j.jvs.2019.02.016. PMID: 31159978Free PMC Article
Ergonomic interventions for preventing work-related musculoskeletal disorders of the upper limb and neck among office workers.
Hoe VC, Urquhart DM, Kelsall HL, Zamri EN, Sim MR
Cochrane Database Syst Rev 2018 Oct 23;10(10):CD008570. doi: 10.1002/14651858.CD008570.pub3. PMID: 30350850Free PMC Article
Heel pain: A systematic review.
Agyekum EK, Ma K
Chin J Traumatol 2015;18(3):164-9. doi: 10.1016/j.cjtee.2015.03.002. PMID: 26643244
Interventions for varicose veins and leg oedema in pregnancy.
Smyth RM, Aflaifel N, Bamigboye AA
Cochrane Database Syst Rev 2015 Oct 19;2015(10):CD001066. doi: 10.1002/14651858.CD001066.pub3. PMID: 26477632Free PMC Article

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