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Cerebral contusion

MedGen UID:
1053012
Concept ID:
CN376650
Finding
HPO: HP:6000141

Definition

A contusion is a region of injured tissue in which blood capillaries have been ruptured without laceration (bruise). Brain contusions are bruises of the cortical surface that damage the surface from the outside inward, producing disruption of tissue and vessels. The term cerebral contusion describes the pathology of focal necrosis and hemorrhage, typically observed in older children, involving particularly cerebral cortex and subcortical white matter. Such lesions are usually found in coup and contrecoup, as well as inferior orbital, frontal, and temporal locations. Cerebral contusions cause permanent damage to tissues of the cerebrum. The etiology of cerebral contusion is trauma to the head. [from HPO]

Professional guidelines

PubMed

Zhang Q, Zhang Y, Meng W, Zhao Y, Zhang J
World Neurosurg 2024 May;185:e1086-e1092. Epub 2024 Mar 14 doi: 10.1016/j.wneu.2024.03.027. PMID: 38490441
Högberg U, Lampa E, Högberg G, Aspelin P, Serenius F, Thiblin I
Eur J Public Health 2018 Aug 1;28(4):641-646. doi: 10.1093/eurpub/cky062. PMID: 29672696Free PMC Article
Rosman NP, Oppenheimer EY, O'Connor JF
Emerg Med Clin North Am 1983 Apr;1(1):141-74. PMID: 6394284

Recent clinical studies

Etiology

Zhang H, Duan X, Zhang Y, Zhuang G, Cao D, Meng W, Yan M, Qi W
Neurocrit Care 2024 Jun;40(3):953-963. Epub 2023 Oct 17 doi: 10.1007/s12028-023-01857-4. PMID: 37848656Free PMC Article
Lin S, Wang Q, Zhu Y, Jin X, Han P, Lu Z
Sci Rep 2022 Nov 29;12(1):20574. doi: 10.1038/s41598-022-24824-z. PMID: 36446999Free PMC Article
Li S, Bai L, Zheng Z
Comput Math Methods Med 2022;2022:4311434. Epub 2022 May 12 doi: 10.1155/2022/4311434. PMID: 35602351Free PMC Article
Zhu Y, Jin X, Xu L, Han P, Lin S, Lu Z
BMC Neurol 2021 Nov 29;21(1):463. doi: 10.1186/s12883-021-02482-4. PMID: 34844563Free PMC Article
Lunøe M, Overgaard-Steensen C
Acta Anaesthesiol Scand 2015 Sep;59(8):975-85. Epub 2015 May 9 doi: 10.1111/aas.12522. PMID: 25960126

Diagnosis

Lin S, Wang Q, Zhu Y, Jin X, Han P, Lu Z
Sci Rep 2022 Nov 29;12(1):20574. doi: 10.1038/s41598-022-24824-z. PMID: 36446999Free PMC Article
Zhu Y, Jin X, Xu L, Han P, Lin S, Lu Z
BMC Neurol 2021 Nov 29;21(1):463. doi: 10.1186/s12883-021-02482-4. PMID: 34844563Free PMC Article
Sindelar B, Bailes JE
Neurol Clin 2017 Aug;35(3):451-472. Epub 2017 May 30 doi: 10.1016/j.ncl.2017.03.006. PMID: 28673409
Jiang JY; Chinese Head Trauma Study Collaborators
Injury 2013 Nov;44(11):1453-7. Epub 2012 Oct 13 doi: 10.1016/j.injury.2012.08.045. PMID: 23068139
Botteri M, Bandera E, Minelli C, Latronico N
Crit Care Med 2008 Nov;36(11):3089-92. doi: 10.1097/CCM.0b013e31818bd7df. PMID: 18824902

Therapy

Zhu Y, Jin X, Xu L, Han P, Lin S, Lu Z
BMC Neurol 2021 Nov 29;21(1):463. doi: 10.1186/s12883-021-02482-4. PMID: 34844563Free PMC Article
McInnis C, Garcia MJS, Widjaja E, Frndova H, Huyse JV, Guerguerian AM, Oyefiade A, Laughlin S, Raybaud C, Miller E, Tay K, Bigler ED, Dennis M, Fraser DD, Campbell C, Choong K, Dhanani S, Lacroix J, Farrell C, Beauchamp MH, Schachar R, Hutchison JS, Wheeler AL
J Neurotrauma 2021 Sep 1;38(17):2407-2418. Epub 2021 May 13 doi: 10.1089/neu.2020.7514. PMID: 33787327
Komori M, Yasaka M, Kokuba K, Matsuoka H, Fujimoto S, Yoshida M, Kameda K, Shono T, Nagata S, Ago T, Kitazono T, Okada Y
Circ J 2014;78(6):1335-41. Epub 2014 Mar 24 doi: 10.1253/circj.cj-13-1534. PMID: 24662438
Seddighi AS, Motiei-Langroudi R, Sadeghian H, Moudi M, Zali A, Asheghi E, Alereza-Amiri R, Seddighi A
Brain Inj 2013;27(13-14):1666-70. Epub 2013 Oct 2 doi: 10.3109/02699052.2013.830333. PMID: 24087934
Braun MM, Patriarca PA, Ellenberg SS
Arch Pediatr Adolesc Med 1997 Mar;151(3):255-9. doi: 10.1001/archpedi.1997.02170400041007. PMID: 9080932

Prognosis

Zhang H, Duan X, Zhang Y, Zhuang G, Cao D, Meng W, Yan M, Qi W
Neurocrit Care 2024 Jun;40(3):953-963. Epub 2023 Oct 17 doi: 10.1007/s12028-023-01857-4. PMID: 37848656Free PMC Article
Lin S, Wang Q, Zhu Y, Jin X, Han P, Lu Z
Sci Rep 2022 Nov 29;12(1):20574. doi: 10.1038/s41598-022-24824-z. PMID: 36446999Free PMC Article
Li S, Bai L, Zheng Z
Comput Math Methods Med 2022;2022:4311434. Epub 2022 May 12 doi: 10.1155/2022/4311434. PMID: 35602351Free PMC Article
Zhu Y, Jin X, Xu L, Han P, Lin S, Lu Z
BMC Neurol 2021 Nov 29;21(1):463. doi: 10.1186/s12883-021-02482-4. PMID: 34844563Free PMC Article
Jiang JY; Chinese Head Trauma Study Collaborators
Injury 2013 Nov;44(11):1453-7. Epub 2012 Oct 13 doi: 10.1016/j.injury.2012.08.045. PMID: 23068139

Clinical prediction guides

Zhang H, Duan X, Zhang Y, Zhuang G, Cao D, Meng W, Yan M, Qi W
Neurocrit Care 2024 Jun;40(3):953-963. Epub 2023 Oct 17 doi: 10.1007/s12028-023-01857-4. PMID: 37848656Free PMC Article
Lin S, Wang Q, Zhu Y, Jin X, Han P, Lu Z
Sci Rep 2022 Nov 29;12(1):20574. doi: 10.1038/s41598-022-24824-z. PMID: 36446999Free PMC Article
Li S, Bai L, Zheng Z
Comput Math Methods Med 2022;2022:4311434. Epub 2022 May 12 doi: 10.1155/2022/4311434. PMID: 35602351Free PMC Article
Zhu Y, Jin X, Xu L, Han P, Lin S, Lu Z
BMC Neurol 2021 Nov 29;21(1):463. doi: 10.1186/s12883-021-02482-4. PMID: 34844563Free PMC Article
Jiang JY; Chinese Head Trauma Study Collaborators
Injury 2013 Nov;44(11):1453-7. Epub 2012 Oct 13 doi: 10.1016/j.injury.2012.08.045. PMID: 23068139

Recent systematic reviews

Wei Y, Cui Y, Pang X, Wang W
Arq Neuropsiquiatr 2024 Apr;82(4):1-10. Epub 2024 Apr 23 doi: 10.1055/s-0044-1785689. PMID: 38653484Free PMC Article
Botteri M, Bandera E, Minelli C, Latronico N
Crit Care Med 2008 Nov;36(11):3089-92. doi: 10.1097/CCM.0b013e31818bd7df. PMID: 18824902

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